Efficient concerted integration by recombinant human immunodeficiency virus type 1 integrase without cellular or viral cofactors.
about
HIV-1 integrase crosslinked oligomers are active in vitroVirological and cellular roles of the transcriptional coactivator LEDGF/p75HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cellsFunctional coupling between HIV-1 integrase and the SWI/SNF chromatin remodeling complex for efficient in vitro integration into stable nucleosomesRetroviral DNA IntegrationHomogeneous high-throughput screening assays for HIV-1 integrase 3beta-processing and strand transfer activities.Fidelity of target site duplication and sequence preference during integration of xenotropic murine leukemia virus-related virus.Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA bindingHIV-1 IN inhibitors: 2010 update and perspectivesPhysical trapping of HIV-1 synaptic complex by different structural classes of integrase strand transfer inhibitors.Cofactors for human immunodeficiency virus type 1 cDNA integration in vitroRetroviral DNA integration: reaction pathway and critical intermediates.Relationship between the oligomeric status of HIV-1 integrase on DNA and enzymatic activity.Retroviral Integrase Structure and DNA Recombination MechanismThe (52-96) C-terminal domain of Vpr stimulates HIV-1 IN-mediated homologous strand transfer of mini-viral DNA.HIV-1 integrase strand transfer inhibitors stabilize an integrase-single blunt-ended DNA complexNucleoprotein intermediates in HIV-1 DNA integration visualized by atomic force microscopyIntasome architecture and chromatin density modulate retroviral integration into nucleosomeChromosomal integration of LTR-flanked DNA in yeast expressing HIV-1 integrase: down regulation by RAD51.Retroviral integration site selection.The HIV-1 integrase monomer induces a specific interaction with LTR DNA for concerted integration.Transcriptional coactivator LEDGF/p75 modulates human immunodeficiency virus type 1 integrase-mediated concerted integration.Nucleoprotein complex intermediates in HIV-1 integrationHost Factors in Retroviral Integration and the Selection of Integration Target Sites.Clinical Use of Inhibitors of HIV-1 Integration: Problems and Prospects.HIV DNA integration.Authentic HIV-1 integrase inhibitors.Characterization of HIV-1 integrase N-terminal mutant viruses.The molecular biology of HIV integrase.Inhibition of human immunodeficiency virus type 1 concerted integration by strand transfer inhibitors which recognize a transient structural intermediateMutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro.The GP(Y/F) domain of TF1 integrase multimerizes when present in a fragment, and substitutions in this domain reduce enzymatic activity of the full-length protein.Structural biology of retroviral DNA integration.Mechanisms of human immunodeficiency virus type 1 concerted integration related to strand transfer inhibition and drug resistance.In vitro initial attachment of HIV-1 integrase to viral ends: control of the DNA specific interaction by the oligomerization state.Integrase, LEDGF/p75 and HIV replication.Structural and functional insights into foamy viral integraseBiochemical and biophysical analyses of concerted (U5/U3) integration.Oligonucleotide-based assays for integrase activity.Integrase and integration: biochemical activities of HIV-1 integrase.
P2860
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P2860
Efficient concerted integration by recombinant human immunodeficiency virus type 1 integrase without cellular or viral cofactors.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Efficient concerted integratio ...... t cellular or viral cofactors.
@en
Efficient concerted integratio ...... t cellular or viral cofactors.
@nl
type
label
Efficient concerted integratio ...... t cellular or viral cofactors.
@en
Efficient concerted integratio ...... t cellular or viral cofactors.
@nl
prefLabel
Efficient concerted integratio ...... t cellular or viral cofactors.
@en
Efficient concerted integratio ...... t cellular or viral cofactors.
@nl
P2093
P2860
P1433
P1476
Efficient concerted integratio ...... t cellular or viral cofactors.
@en
P2093
Duane P Grandgenett
Michael H Pursley
Sapna Sinha
P2860
P304
P356
10.1128/JVI.76.7.3105-3113.2002
P407
P577
2002-04-01T00:00:00Z