The pseudorabies virus VP22 homologue (UL49) is dispensable for virus growth in vitro and has no effect on virulence and neuronal spread in rodents.
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Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine.Tegument Assembly and Secondary Envelopment of AlphaherpesvirusesNuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infectionIdentification and characterization of the pseudorabies virus tegument proteins UL46 and UL47: role for UL47 in virion morphogenesis in the cytoplasm.Affimer proteins are versatile and renewable affinity reagentsActin is a component of the compensation mechanism in pseudorabies virus virions lacking the major tegument protein VP22.Host cell targets of tegument protein VP22 of herpes simplex virus 1.Deletion of the herpes simplex virus VP22-encoding gene (UL49) alters the expression, localization, and virion incorporation of ICP0.Characterization of VP22 in herpes simplex virus-infected cells.A virulent bioluminescent and fluorescent dual-reporter Marek's disease virus unveils an alternative spreading pathway in addition to cell-to-cell contact.Sequential localization of two herpes simplex virus tegument proteins to punctate nuclear dots adjacent to ICP0 domainsPhysical interaction between envelope glycoproteins E and M of pseudorabies virus and the major tegument protein UL49.Characterization of a UL49-null mutant: VP22 of herpes simplex virus type 1 facilitates viral spread in cultured cells and the mouse corneaHerpes simplex virus glycoproteins gD and gE/gI serve essential but redundant functions during acquisition of the virion envelope in the cytoplasm.Cell cycle modulation by Marek's disease virus: the tegument protein VP22 triggers S-phase arrest and DNA damage in proliferating cells.The ubiquitous cellular transcriptional factor USF targets the varicella-zoster virus open reading frame 10 promoter and determines virulence in human skin xenografts in SCIDhu mice in vivo.Herpes simplex virus 1 VP22 regulates translocation of multiple viral and cellular proteins and promotes neurovirulence.Marek's disease virus expresses multiple UL44 (gC) variants through mRNA splicing that are all required for efficient horizontal transmission.Virion-wide protein interactions of Kaposi's sarcoma-associated herpesvirusORF9p phosphorylation by ORF47p is crucial for the formation and egress of varicella-zoster virus viral particles.The role of the cytoskeleton in the life cycle of viruses and intracellular bacteria: tracks, motors, and polymerization machines.Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: differentiation and structural integration into the segmental motor circuitryAlphaherpesviruses and the cytoskeleton in neuronal infections.Functions of the ORF9-to-ORF12 gene cluster in varicella-zoster virus replication and in the pathogenesis of skin infectionAnalysis of viral and cellular factors influencing herpesvirus-induced nuclear envelope breakdownThe UL48 tegument protein of pseudorabies virus is critical for intracytoplasmic assembly of infectious virionsThe attenuated pseudorabies virus strain Bartha fails to package the tegument proteins Us3 and VP22.A self-excisable infectious bacterial artificial chromosome clone of varicella-zoster virus allows analysis of the essential tegument protein encoded by ORF9.The capsid and tegument of the alphaherpesviruses are linked by an interaction between the UL25 and VP1/2 proteins.The pseudorabies virus Us2 protein, a virion tegument component, is prenylated in infected cells.A pseudorabies virus recombinant simultaneously lacking the major tegument proteins encoded by the UL46, UL47, UL48, and UL49 genes is viable in cultured cells.Essential function of the pseudorabies virus UL36 gene product is independent of its interaction with the UL37 protein.Fluorescent tagging of VP22 in N-terminus reveals that VP22 favors Marek's disease virus (MDV) virulence in chickens and allows morphogenesis study in MD tumor cells.Morphogenesis of a highly replicative EGFPVP22 recombinant Marek's disease virus in cell culture.Heterogeneity of a fluorescent tegument component in single pseudorabies virus virions and enveloped axonal assemblies.Functional homologies between avian and human alphaherpesvirus VP22 proteins in cell-to-cell spreading as revealed by a new cis-complementation assay.Varicella-Zoster Virus ORF9p Binding to Cellular Adaptor Protein Complex 1 Is Important for Viral Infectivity
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P2860
The pseudorabies virus VP22 homologue (UL49) is dispensable for virus growth in vitro and has no effect on virulence and neuronal spread in rodents.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The pseudorabies virus VP22 ho ...... nd neuronal spread in rodents.
@en
The pseudorabies virus VP22 homologue
@nl
type
label
The pseudorabies virus VP22 ho ...... nd neuronal spread in rodents.
@en
The pseudorabies virus VP22 homologue
@nl
prefLabel
The pseudorabies virus VP22 ho ...... nd neuronal spread in rodents.
@en
The pseudorabies virus VP22 homologue
@nl
P2093
P2860
P1433
P1476
The pseudorabies virus VP22 ho ...... nd neuronal spread in rodents.
@en
P2093
H C Werner
L W Enquist
P2860
P304
P356
10.1128/JVI.76.2.774-782.2002
P407
P577
2002-01-01T00:00:00Z