Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint.
about
Prp8 protein: at the heart of the spliceosomeThe Saccharomyces cerevisiae gene CDC40/PRP17 controls cell cycle progression through splicing of the ANC1 geneNtc90 is required for recruiting first step factor Yju2 but not for spliceosome activation.Upregulation of SYF2 is associated with neuronal apoptosis caused by reactive astrogliosis to neuroinflammationDisruption of murine mp29/Syf2/Ntc31 gene results in embryonic lethality with aberrant checkpoint responseMalleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome.Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair.Systematic profiling of cellular phenotypes with spotted cell microarrays reveals mating-pheromone response genesCell cycle abnormalities associated with differential perturbations of the human U5 snRNP associated U5-200kD RNA helicase.Suppressors of the cdc-25.1(gf)-associated intestinal hyperplasia reveal important maternal roles for prp-8 and a subset of splicing factors in C. elegans.Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome.SYF2 is upregulated in human epithelial ovarian cancer and promotes cell proliferation.Knocking down the expression of SYF2 inhibits the proliferation of glioma cells.Dependence of pre-mRNA introns on PRP17, a non-essential splicing factor: implications for efficient progression through cell cycle transitions.Regulation of Cdc2p and Cdc13p is required for cell cycle arrest induced by defective RNA splicing in fission yeast.Overexpression of SYF2 correlates with enhanced cell growth and poor prognosis in human hepatocellular carcinoma.Graded requirement for the spliceosome in cell cycle progressionInactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defects.Upregulation of SYF2 in esophageal squamous cell carcinoma promotes tumor cell proliferation and predicts poor prognosis.Overexpression of SYF2 promotes cell proliferation and correlates with poor prognosis in human breast cancer.Intron specificity in pre-mRNA splicing.Involvement of upregulated SYF2 in Schwann cell differentiation and migration after sciatic nerve crush.Upregulation of SYF2 Relates to Retinal Ganglion Cell Apoptosis and Retinal Glia Cell Proliferation After Light-Induced Retinal Damage.Therapy-induced stress response is associated with downregulation of pre-mRNA splicing in cancer cells.
P2860
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P2860
Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Mutations in genes of Saccharo ...... ion of the spindle checkpoint.
@en
Mutations in genes of Saccharo ...... ion of the spindle checkpoint.
@nl
type
label
Mutations in genes of Saccharo ...... ion of the spindle checkpoint.
@en
Mutations in genes of Saccharo ...... ion of the spindle checkpoint.
@nl
prefLabel
Mutations in genes of Saccharo ...... ion of the spindle checkpoint.
@en
Mutations in genes of Saccharo ...... ion of the spindle checkpoint.
@nl
P2860
P356
P1476
Mutations in genes of Saccharo ...... ion of the spindle checkpoint.
@en
P2093
Martin Kupiec
Orna Dahan
P2860
P304
P356
10.1093/NAR/GKF563
P407
P577
2002-10-01T00:00:00Z