L1CAM-integrin interaction induces constitutive NF-kappaB activation in pancreatic adenocarcinoma cells by enhancing IL-1beta expression.
about
Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.L1CAM in human cancer.L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer.Generation, characterization and preclinical studies of a human anti-L1CAM monoclonal antibody that cross-reacts with rodent L1CAMVariations of oral microbiota are associated with pancreatic diseases including pancreatic cancerL1cam promotes tumor progression and metastasis and is an independent unfavorable prognostic factor in gastric cancerCharacterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer.Prognostic value and clinicopathologic characteristics of L1 cell adhesion molecule (L1CAM) in a large series of vulvar squamous cell carcinomas.Downregulation of L1CAM inhibits proliferation, invasion and arrests cell cycle progression in pancreatic cancer cells in vitroNF-κB as a target for pancreatic cancer therapy.L1CAM: a major driver for tumor cell invasion and motility.The malignant social network: cell-cell adhesion and communication in cancer stem cellsThe immune network in pancreatic cancer development and progression.L1 cell adhesion molecule as a therapeutic target in cancer.c-Rel is a critical mediator of NF-κB-dependent TRAIL resistance of pancreatic cancer cells.L1CAM promotes enrichment of immunosuppressive T cells in human pancreatic cancer correlating with malignant progression.EMT-associated up-regulation of L1CAM provides insights into L1CAM-mediated integrin signalling and NF-κB activation.CD24 controls Src/STAT3 activity in human tumors.Prognostic significance of L1CAM in ovarian cancer and its role in constitutive NF-κB activation.The 'N-factors' in pancreatic cancer: functional relevance of NF-κB, NFAT and Nrf2 in pancreatic cancer.Integrin signaling in cancer cell survival and chemoresistanceL1CAM drives oncogenicity in esophageal squamous cell carcinoma by stimulation of ezrin transcription.Tumor-stroma IL-1β-IRAK4 feedforward circuitry drives tumor fibrosis, chemoresistance, and poor prognosis in pancreatic cancer.A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis.
P2860
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P2860
L1CAM-integrin interaction induces constitutive NF-kappaB activation in pancreatic adenocarcinoma cells by enhancing IL-1beta expression.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
L1CAM-integrin interaction ind ...... enhancing IL-1beta expression.
@en
L1CAM-integrin interaction ind ...... enhancing IL-1beta expression.
@nl
type
label
L1CAM-integrin interaction ind ...... enhancing IL-1beta expression.
@en
L1CAM-integrin interaction ind ...... enhancing IL-1beta expression.
@nl
prefLabel
L1CAM-integrin interaction ind ...... enhancing IL-1beta expression.
@en
L1CAM-integrin interaction ind ...... enhancing IL-1beta expression.
@nl
P2093
P356
P1433
P1476
L1CAM-integrin interaction ind ...... enhancing IL-1beta expression.
@en
P2093
N Erbe-Hoffmann
P Altevogt
S Sebens Müerköster
P2860
P2888
P304
P356
10.1038/ONC.2010.230
P407
P577
2010-06-14T00:00:00Z