Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage.
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Pathophysiology of cutaneous lupus erythematosusTranscriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptationTLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathwaysFos-dependent induction of Chk1 protects osteoblasts from replication stressAdaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations.The 3'-5' DNA exonuclease TREX1 directly interacts with poly(ADP-ribose) polymerase-1 (PARP1) during the DNA damage response.Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis.The role of DNA exonucleases in protecting genome stability and their impact on ageing.Rare variants in the TREX1 gene and susceptibility to autoimmune diseasesApoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity.Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1.Insights Gained From the Study of Pediatric Systemic Lupus Erythematosus.
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P2860
Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage.
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2010 nî lūn-bûn
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name
Three prime exonuclease I (TRE ...... o(a)pyrene-induced DNA damage.
@en
Three prime exonuclease I
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type
label
Three prime exonuclease I (TRE ...... o(a)pyrene-induced DNA damage.
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Three prime exonuclease I
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Three prime exonuclease I (TRE ...... o(a)pyrene-induced DNA damage.
@en
Three prime exonuclease I
@nl
P2093
P2860
P356
P1476
Three prime exonuclease I (TRE ...... o(a)pyrene-induced DNA damage.
@en
P2093
Bernd Kaina
Dorthe Aasland
Maja T Tomicic
Markus Christmann
Nicole Berdelle
P2860
P304
P356
10.1093/NAR/GKQ455
P407
P577
2010-05-28T00:00:00Z