Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives.
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Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics SimulationsCancer cells acquire mitotic drug resistance properties through beta I-tubulin mutations and alterations in the expression of beta-tubulin isotypesTargeting Toxoplasma tubules: tubulin, microtubules, and associated proteins in a human pathogen6-Methoxy Podophyllotoxin Induces Apoptosis via Inhibition of TUBB3 and TOPIIA Gene Expressions in 5637 and K562 Cancer Cell Lines.Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy.Determination of the optimal tubulin isotype target as a method for the development of individualized cancer chemotherapyThe tubulin colchicine domain: a molecular modeling perspective.Tubulin-interactive stilbene derivatives as anticancer agents.Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer.Effect of CH-35, a novel anti-tumor colchicine analogue, on breast cancer cells overexpressing the βIII isotype of tubulin.Measuring the persistence length of MCF7 cell microtubules in vitro.Aptamers as both drugs and drug-carriers.Experimental and computational study of the interaction of novel colchicinoids with a recombinant human αI/βI-tubulin heterodimer.Increased α-tubulin1b expression indicates poor prognosis and resistance to chemotherapy in hepatocellular carcinoma.A tripartite mode of action approach for investigating the impact of aneugens on tubulin polymerization.Nanoformulations of albendazole as effective anticancer and antiparasite agents.Structural investigations into the binding mode of a novel noscapine analogue, 9-(4-vinylphenyl) noscapine, with tubulin by biochemical analyses and molecular dynamic simulations.
P2860
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P2860
Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
@zh-hant
name
Quantitative analysis of the e ...... novel colchicine derivatives.
@en
Quantitative analysis of the e ...... novel colchicine derivatives.
@nl
type
label
Quantitative analysis of the e ...... novel colchicine derivatives.
@en
Quantitative analysis of the e ...... novel colchicine derivatives.
@nl
prefLabel
Quantitative analysis of the e ...... novel colchicine derivatives.
@en
Quantitative analysis of the e ...... novel colchicine derivatives.
@nl
P2093
P2860
P356
P1433
P1476
Quantitative analysis of the e ...... novel colchicine derivatives.
@en
P2093
Chih-Yuan Tseng
Elzbieta Izbicka
Jack A Tuszynski
Jonathan Y Mane
Lorelei Johnson
Philip Winter
Richard F Luduena
Torin Huzil
P2860
P2888
P356
10.1186/1476-4598-9-131
P577
2010-05-30T00:00:00Z
P5875
P6179
1026965661