Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.
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Wnt signaling pathway in non-small cell lung cancerFrizzled homolog proteins, microRNAs and Wnt signaling in cancerMetastasis suppressor genes at the interface between the environment and tumor cell growthEffects of valproic acid and pioglitazone on cell cycle progression and proliferation of T-cell acute lymphoblastic leukemia Jurkat cellsA bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrainH3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma.K-homology splicing regulatory protein (KSRP) promotes post-transcriptional destabilization of Spry4 transcripts in non-small cell lung cancer.Genome-wide analysis of long noncoding RNA and mRNA co-expression profile in intrahepatic cholangiocarcinoma tissue by RNA sequencing.The developing story of Sprouty and cancer.Peripheral T-lymphocytes express WNT7A and its restoration in leukemia-derived lymphoblasts inhibits cell proliferation.Keratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells.Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis.Sprouty is a negative regulator of transforming growth factor β-induced epithelial-to-mesenchymal transition and cataract.Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract.MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.Initial report on differential expression of sprouty proteins 1 and 2 in human epithelial ovarian cancer cell lines.Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells.Suppression of Spry1 inhibits triple-negative breast cancer malignancy by decreasing EGF/EGFR mediated mesenchymal phenotype.Non-small-cell lung cancer: molecular targeted therapy and personalized medicine - drug resistance, mechanisms, and strategiesTargeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility.Long noncoding RNAs: new insights into non-small cell lung cancer biology, diagnosis and therapy.Sprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.The soft agar colony formation assay.Sprouty4 interferes with cell proliferation and migration of breast cancer-derived cell lines.Sprouty2 but not Sprouty4 is a potent inhibitor of cell proliferation and migration of osteosarcoma cells.Long Non-Coding RNAs: Key Regulators of Epithelial-Mesenchymal Transition, Tumour Drug Resistance and Cancer Stem Cells.Expression profile of genes regulated by curcumin in Y79 retinoblastoma cells.SPRY4-IT1: A novel oncogenic long non-coding RNA in human cancers.Sprouty 2 protein, but not Sprouty 4, is an independent prognostic biomarker for human epithelial ovarian cancer.Sprouty4 mRNA variants and protein expressions in breast and lung-derived cells.The role of SMAD3 in the genetic predisposition to papillary thyroid carcinoma.Knockdown of SPRY4 and SPRY4-IT1 inhibits cell growth and phosphorylation of Akt in human testicular germ cell tumours.Downregulation of CSN6 attenuates papillary thyroid carcinoma progression by reducing Wnt/β-catenin signaling and sensitizes cancer cells to FH535 therapy.Investigation of six testicular germ cell tumor susceptibility genes suggests a parent-of-origin effect in SPRY4.
P2860
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P2860
Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Sprouty-4 inhibits transformed ...... in non-small cell lung cancer.
@en
Sprouty-4 inhibits transformed ...... in non-small cell lung cancer.
@nl
type
label
Sprouty-4 inhibits transformed ...... in non-small cell lung cancer.
@en
Sprouty-4 inhibits transformed ...... in non-small cell lung cancer.
@nl
prefLabel
Sprouty-4 inhibits transformed ...... in non-small cell lung cancer.
@en
Sprouty-4 inhibits transformed ...... in non-small cell lung cancer.
@nl
P2093
P2860
P1476
Sprouty-4 inhibits transformed ...... in non-small cell lung cancer.
@en
P2093
Katherine M Vandervest
Meredith A Tennis
Michelle M Van Scoyk
Raphael A Nemenoff
Robert A Winn
Scott V Freeman
P2860
P304
P356
10.1158/1541-7786.MCR-09-0400
P577
2010-05-25T00:00:00Z