Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
about
Human isoprenoid synthase enzymes as therapeutic targetsReconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INITGGPPS1 predicts the biological character of hepatocellular carcinoma in patients with cirrhosisXanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss.In vitro studies in a myelogenous leukemia cell line suggest an organized binding of geranylgeranyl diphosphate synthase inhibitorsIn vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.Metabolic and protein interaction sub-networks controlling the proliferation rate of cancer cells and their impact on patient survival.Targeting protein geranylgeranylation slows tumor development in a murine model of prostate cancer metastasis.The interplay between mutant p53 and the mevalonate pathway.Overexpression of geranylgeranyl diphosphate synthase contributes to tumour metastasis and correlates with poor prognosis of lung adenocarcinoma.Cancer cell metabolism as new targets for novel designed therapies
P2860
Q26822639-31545872-584A-41E6-842B-83411C9C80D6Q28483779-12999778-A0F1-425E-AE70-C1893E02FC93Q33638516-E26EEEFD-6C6D-4BAB-8015-28CD4F1FAFEBQ36197808-0369983B-6283-49A8-A862-B637B491FE80Q38878009-B060E67C-C66F-4C3F-9011-84A5DF605562Q38968601-D2C10F50-C72E-4E14-BD87-8B42A921B75EQ39072239-D00DC144-957C-4365-BC7F-BEBB611DF1F5Q47138834-06A7F97D-854D-4C66-88D5-466CEC5BAE93Q47296038-3C75E593-31F2-4A84-9B57-3D9D0C1830E0Q47645395-4FF43338-B2E0-4F59-A524-BDD33A462F2DQ56994128-A2846395-15AB-449C-B190-03A16B0E8EE4
P2860
Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
@en
Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
@nl
type
label
Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
@en
Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
@nl
prefLabel
Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
@en
Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
@nl
P2093
P2860
P1476
Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
@en
P2093
Amel Dudakovic
Huaxiang Tong
Raymond J Hohl
P2860
P2888
P304
P356
10.1007/S10637-010-9446-Y
P577
2010-05-18T00:00:00Z