The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells. - Wikidata - awgldk - TriplyDB

The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells.

The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells.

http://www.wikidata.org/entity/Q39705415

about

Salinomycin as a drug for targeting human cancer stem cells Autophagy in stem cells.Regulation of ovarian cancer stem cells or tumor-initiating cells Chemoquiescence for ideal cancer treatment and prevention: where are we now?Insulin-Sensitizers, Polycystic Ovary Syndrome and Gynaecological Cancer Risk On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells Response of breast cancer cells and cancer stem cells to metformin and hyperthermia alone or combined AMPK activation--protean potential for boosting healthspan.Biomarkers to Target Heterogeneous Breast Cancer Stem Cells Understanding the benefit of metformin use in cancer treatment.Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention.Targeting miRNAs involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance.Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells.Primary trastuzumab resistance: new tricks for an old drug.The complexities of obesity and diabetes with the development and progression of pancreatic cancer.Human epidermal growth factor receptor-2-positive breast cancer: Current management of early, advanced, and recurrent disease.Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression.Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics Gerosuppressant metformin: less is more Metabolic Syndrome and Breast Cancer Risk: Is There a Role for Metformin?Maintenance Therapy Containing Metformin and/or Zyflamend for Advanced Prostate Cancer: A Case Series In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.Curcumin Improves the Tumoricidal Effect of Mitomycin C by Suppressing ABCG2 Expression in Stem Cell-Like Breast Cancer Cells.Metformin: multi-faceted protection against cancer.Phenolic secoiridoids in extra virgin olive oil impede fibrogenic and oncogenic epithelial-to-mesenchymal transition: extra virgin olive oil as a source of novel antiaging phytochemicals.Metformin selectively targets tumor-initiating cells in ErbB2-overexpressing breast cancer models.Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells Metformin: an emerging new therapeutic option for targeting cancer stem cells and metastasis Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts.Metformin Treatment for the Prevention and/or Treatment of Breast/Mammary Tumorigenesis Cancer risk in HBV patients with statin and metformin use: a population-based cohort study.Importance of CD200 expression by tumor or host cells to regulation of immunotherapy in a mouse breast cancer model.Screening of breast cancer stem cell inhibitors using a protein kinase inhibitor library.The role of cancer stem cells in breast cancer initiation and progression: potential cancer stem cell-directed therapies.Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1 Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin).

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The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells.

http://www.wikidata.org/entity/Q39705415

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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2010年學術文章

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2010年學術文章

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name

The anti-diabetic drug metform ...... ting breast cancer stem cells.

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The anti-diabetic drug metform ...... ting breast cancer stem cells.

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type

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The anti-diabetic drug metform ...... ting breast cancer stem cells.

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The anti-diabetic drug metform ...... ting breast cancer stem cells.

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The anti-diabetic drug metform ...... ting breast cancer stem cells.

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The anti-diabetic drug metform ...... ting breast cancer stem cells.

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Breast Cancer Research and Treatment

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The anti-diabetic drug metform ...... ting breast cancer stem cells.

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Alejandro Vazquez-Martin

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Cristina Oliveras-Ferraros

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Javier A Menendez

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Sonia Del Barco

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P2860

The CD44+/CD24- phenotype is enriched in basal-like breast tumors

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

Prospective identification of tumorigenic breast cancer cells

Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

Metformin: a therapeutic opportunity in breast cancer.

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission.

CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis

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Begoña Martin-Castillo

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