GSK3 beta regulates myelin-dependent axon outgrowth inhibition through CRMP4.
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GSK-3 Inhibitors: Preclinical and Clinical Focus on CNSPTEN inhibition and axon regeneration and neural repairGSK3 regulates mitotic chromosomal alignment through CRMP4Crystal structure of human CRMP-4: correction of intensities for lattice-translocation disorderGSK-3: Functional Insights from Cell Biology and Animal Models.Beneficial compaction of spinal cord lesion by migrating astrocytes through glycogen synthase kinase-3 inhibition.Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2.The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP.Crmp4 deletion promotes recovery from spinal cord injury by neuroprotection and limited scar formation.Collapsin response mediator proteins regulate neuronal development and plasticity by switching their phosphorylation status.Collapsin response mediator protein 4 regulates growth cone dynamics through the actin and microtubule cytoskeleton.Sevoflurane induces short-term changes in proteins in the cerebral cortices of developing rats.CDK5 activator protein p25 preferentially binds and activates GSK3βChemical interrogation of the neuronal kinome using a primary cell-based screening assay.Chronic exposure to light reverses the effect of maternal separation on proteins in the prefrontal cortex.What Are the bona fide GSK3 Substrates?Poly(trimethylene carbonate-co-ε-caprolactone) promotes axonal growth.CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon ElongationExtrinsic and intrinsic determinants of nerve regenerationThe Acquisition of Target Dependence by Developing Rat Retinal Ganglion Cells(1,2,3).Heterogeneous intrastriatal pattern of proteins regulating axon growth in normal adult human brain.Activating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTOR in vivo.Targeting CRMP-4 by lentivirus-mediated RNA interference inhibits SW480 cell proliferation and colorectal cancer growthDihydropyrimidinase-like protein 3 expression is negatively regulated by MYCN and associated with clinical outcome in neuroblastomaCombined application of Rho-ROCKII and GSK-3β inhibitors exerts an improved protective effect on axonal regeneration in rats with spinal cord injury.Spinal cord injury therapies in humans: an overview of current clinical trials and their potential effects on intrinsic CNS macrophages.PI3 Kinase regulation of neural regeneration and muscle hypertrophy after spinal cord injury.Role of GSK3 Signaling in Neuronal Morphogenesis.The role of Nogo-A in axonal plasticity, regrowth and repair.Nogo-A represses anatomical and synaptic plasticity in the central nervous system.Neuronal cytoskeleton in synaptic plasticity and regeneration.Glycogen synthase kinase 3 beta (GSK3β) at the tip of neuronal development and regeneration.Postnatal alteration of collapsin response mediator protein 4 mRNA expression in the mouse brain.Function of Nogo-A/Nogo-A receptor in Alzheimer's disease.Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity.CRMPs Function in Neurons and Glial Cells: Potential Therapeutic Targets for Neurodegenerative Diseases and CNS Injury.Molecular mechanisms underlying the positive role of treadmill training in locomotor recovery after spinal cord injury.Role of glycogen synthase kinase following myocardial infarction and ischemia-reperfusion.Inhibition of gecko GSK-3β promotes elongation of neurites and oligodendrocyte processes but decreases the proliferation of blastemal cells.Deletion of collapsin response mediator protein 4 results in abnormal layer thickness and elongation of mitral cell apical dendrites in the neonatal olfactory bulb.
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P2860
GSK3 beta regulates myelin-dependent axon outgrowth inhibition through CRMP4.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
GSK3 beta regulates myelin-dependent axon outgrowth inhibition through CRMP4.
@en
GSK3 beta regulates myelin-dependent axon outgrowth inhibition through CRMP4.
@nl
type
label
GSK3 beta regulates myelin-dependent axon outgrowth inhibition through CRMP4.
@en
GSK3 beta regulates myelin-dependent axon outgrowth inhibition through CRMP4.
@nl
prefLabel
GSK3 beta regulates myelin-dependent axon outgrowth inhibition through CRMP4.
@en
GSK3 beta regulates myelin-dependent axon outgrowth inhibition through CRMP4.
@nl
P2093
P1476
GSK3 beta regulates myelin-dependent axon outgrowth inhibition through CRMP4
@en
P2093
Alyson E Fournier
Madeline Pool
Stephan Ong Tone
Yazan Z Alabed
P304
P356
10.1523/JNEUROSCI.6154-09.2010
P407
P577
2010-04-01T00:00:00Z