Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis. - Wikidata - awgldk - TriplyDB

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

http://www.wikidata.org/entity/Q39715299

about

Escaping Deleterious Immune Response in Their Hosts: Lessons from Trypanosomatids A current analysis of chemotherapy strategies for the treatment of human African trypanosomiasis tRNAs as antibiotic targets Metalloid compounds as drugs Benzoxaborole as a new chemotype for carbonic anhydrase inhibition Characterization of the Dynamic Equilibrium between Closed and Open Forms of the Benzoxaborole Pharmacophore.Synthesis and evaluation of functionalized benzoboroxoles as potential anti-tuberculosis agents.Challenges and opportunities in developing novel drugs for TB.Proteomics: a new way to improve human African trypanosomiasis diagnosis?Potential new clinical therapies for Chagas disease.Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015).Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.Synthesis and study of antibacterial activities of antibacterial glycopeptide antibiotics conjugated with benzoxaboroles.Drugs for Neglected Diseases initiative model of drug development for neglected diseases: current status and future challenges.Ring Structure and Aromatic Substituent Effects on the pK a of the Benzoxaborole Pharmacophore.Organocatalytic, enantioselective synthesis of benzoxaboroles via Wittig/oxa-Michael reaction Cascade of α-formyl boronic acids.Drugs for neglected diseases: part I.Focusing on boron in medicinal chemistry.Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.Interview with Future Medicinal Chemistry's US Senior Editor, Iwao Ojima. Interview by Issac Bruce.Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles.Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles.Recent updates in the discovery and development of novel antimalarial drug candidates Clinical and veterinary trypanocidal benzoxaboroles target CPSF3 Novel lead compounds in pre-clinical development against African sleeping sickness

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P2860

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

http://www.wikidata.org/entity/Q39715299

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

@en

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

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type

label

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

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Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

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prefLabel

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

@en

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

@nl

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P1433

Future Medicinal Chemistry

P1476

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

@en

P2093

Bakela Nare

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Cyrus J Bacchi

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Daitao Chen

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Eric G Gaukel

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Jacob J Plattner

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Jessica M Sligar

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Joe B Perales

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Matthew D Orr

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Matthew Jenks

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Nigel Yarlett

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P2860

SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis

An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial

Nifurtimox plus Eflornithine for late-stage sleeping sickness in Uganda: a case series

NECT is next: implementing the new drug combination therapy for Trypanosoma brucei gambiense sleeping sickness

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Drug-like properties and the causes of poor solubility and poor permeability.

Eliminating human African trypanosomiasis: where do we stand and what comes next?

The burden of human African trypanosomiasis

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

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1259-1278

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10.4155/FMC.11.80

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10

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3

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51588068

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21859301

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African trypanosomiasis

trypanosomiasis