Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells.
about
Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator functionMelanoma Cancer Stem Cells: Markers and FunctionsMicrobubble array diffusion assay for the detection of cell secreted factors.SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells.Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation.Natural compounds' activity against cancer stem-like or fast-cycling melanoma cells.Gene expression profiling identifies microphthalmia-associated transcription factor (MITF) and Dickkopf-1 (DKK1) as regulators of microenvironment-driven alterations in melanoma phenotypeSystematic identification of signaling pathways with potential to confer anticancer drug resistance.MITF in melanoma: mechanisms behind its expression and activity.Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanomaMCL-1, BCL-XL and MITF Are Diversely Employed in Adaptive Response of Melanoma Cells to Changes in Microenvironment.Host-derived pericytes and Sca-1+ cells predominate in the MART-1- stroma fraction of experimentally induced melanoma.Initiate Tumors with Single Cell Spheres Formed in Serum-Containing Medium.Tyrosine kinase inhibitor SU11274 increased tumorigenicity and enriched for melanoma-initiating cells by bioenergetic modulation.The early antitumor immune response is necessary for tumor growth: Re-visiting Prehn's hypothesis in the human melanoma system.Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres.MiRNA Transcriptome Profiling of Spheroid-Enriched Cells with Cancer Stem Cell Properties in Human Breast MCF-7 Cell Line.In vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals.Differential mechanisms of tumor progression in clones from a single heterogeneous human melanoma.Mek inhibition results in marked antitumor activity against metastatic melanoma patient-derived melanospheres and in melanosphere-generated xenografts.Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/β-catenin signaling.Lunasin is a novel therapeutic agent for targeting melanoma cancer stem cells.Drug treatment of cancer cell lines: a way to select for cancer stem cells?Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to ΔPK oncolytic activity in melanoma.Honokiol inhibits melanoma stem cells by targeting notch signaling.CD133 Is Not Suitable Marker for Isolating Melanoma Stem Cells from D10 Cell Line.The oncolytic virus ΔPK has multimodal anti-tumor activity.Single-cell gene expression signatures reveal melanoma cell heterogeneity.The multifaceted role of CD146/MCAM in the promotion of melanoma progression.Cancer Stem Cells (CSCs) in melanoma: There's smoke, but is there fire?Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells.Gene expression changes in melanoma metastases in response to high-dose chemotherapy during isolated limb perfusion.Nanog and Oct4 overexpression increases motility and transmigration of melanoma cells.Stem cell media culture of melanoma results in the induction of a nonrepresentative neural expression profile.Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathwayImmunomodulatory Factors Control the Fate of Melanoma Tumor Initiating Cells.The in vitro spheroid melanoma cell culture assay: cues on tumor initiation?Null ABCA3 in humans: large homozygous ABCA3 deletion, correlation to clinical-pathological findings.Tumor-initiating properties of breast cancer and melanoma cells in vivo are not invariably reflected by spheroid formation in vitro, but can be increased by long-term culturing as adherent monolayers.Culture and isolation of melanoma-initiating cells.
P2860
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P2860
Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Heterogeneous phenotype of hum ...... res of tumor-initiating cells.
@en
Heterogeneous phenotype of hum ...... res of tumor-initiating cells.
@nl
type
label
Heterogeneous phenotype of hum ...... res of tumor-initiating cells.
@en
Heterogeneous phenotype of hum ...... res of tumor-initiating cells.
@nl
prefLabel
Heterogeneous phenotype of hum ...... res of tumor-initiating cells.
@en
Heterogeneous phenotype of hum ...... res of tumor-initiating cells.
@nl
P2093
P356
P1476
Heterogeneous phenotype of hum ...... res of tumor-initiating cells.
@en
P2093
Antonello Villa
Antonino Carbone
Chiara Castelli
Gabrina Tragni
Giacomo Cossa
Giorgio Parmiani
Graziella Pratesi
Luigi Mariani
Malcolm R Alison
Maria G Daidone
P2888
P304
P356
10.1038/JID.2010.69
P407
P577
2010-04-08T00:00:00Z