Development and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions.
about
DNA polymerase family X: function, structure, and cellular rolesMicrosatellite interruptions stabilize primate genomes and exist as population-specific single nucleotide polymorphisms within individual human genomesMutational clusters generated by non-processive polymerases: A case study using DNA polymerase betain vitroWhat is a microsatellite: a computational and experimental definition based upon repeat mutational behavior at A/T and GT/AC repeatsTelomeric repeat mutagenicity in human somatic cells is modulated by repeat orientation and G-quadruplex stability.The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis.Genetic evidence that both dNTP-stabilized and strand slippage mechanisms may dictate DNA polymerase errors within mononucleotide microsatellites.Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability.Loop II of DNA polymerase beta is important for polymerization activity and fidelity.The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 cells.DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequencesMature microsatellites: mechanisms underlying dinucleotide microsatellite mutational biases in human cells.Distinct mutational behaviors differentiate short tandem repeats from microsatellites in the human genomeThe human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation.The E249K mutator mutant of DNA polymerase beta extends mispaired termini.Threonine 79 is a hinge residue that governs the fidelity of DNA polymerase beta by helping to position the DNA within the active site.Mutational analyses of dinucleotide and tetranucleotide microsatellites in Escherichia coli: influence of sequence on expansion mutagenesis.Mutation rate and specificity analysis of tetranucleotide microsatellite DNA alleles in somatic human cells.Loop II of DNA polymerase beta is important for discrimination during substrate binding.Dysfunctional proofreading in the Escherichia coli DNA polymerase III core.The mutational specificity of the Dbh lesion bypass polymerase and its implications.Error-prone processing of apurinic/apyrimidinic (AP) sites by PolX underlies a novel mechanism that promotes adaptive mutagenesis in Bacillus subtilis.Escherichia coli DNA polymerase IV contributes to spontaneous mutagenesis at coding sequences but not microsatellite alleles.The 3' --> 5' exonuclease of T4 DNA polymerase removes premutagenic alkyl mispairs and contributes to futile cycling at O6-methylguanine lesions.DNA polymerase kappa microsatellite synthesis: two distinct mechanisms of slippage-mediated errors.
P2860
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P2860
Development and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Development and use of an in v ...... ocessing of DNA alkyl lesions.
@en
Development and use of an in v ...... ocessing of DNA alkyl lesions.
@nl
type
label
Development and use of an in v ...... ocessing of DNA alkyl lesions.
@en
Development and use of an in v ...... ocessing of DNA alkyl lesions.
@nl
prefLabel
Development and use of an in v ...... ocessing of DNA alkyl lesions.
@en
Development and use of an in v ...... ocessing of DNA alkyl lesions.
@nl
P2093
P2860
P356
P1476
Development and use of an in v ...... ocessing of DNA alkyl lesions.
@en
P2093
P2860
P304
P356
10.1093/NAR/25.7.1450
P407
P577
1997-04-01T00:00:00Z