Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine.
about
Integrated analysis of drug-induced gene expression profiles predicts novel hERG inhibitorsHERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cellsAntidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG.In vitro chronic effects on hERG channel caused by the marine biotoxin azaspiracid-2.QTc interval prolongation with vascular endothelial growth factor receptor tyrosine kinase inhibitors.Molecular determinants of pentamidine-induced hERG trafficking inhibition.Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cellsMechanisms of Cardiotoxicity of Cancer Chemotherapeutic Agents: Cardiomyopathy and Beyond.Role of ion transport in control of apoptotic cell death.hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine.Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels.
P2860
Q28534789-79331DD9-2073-4FBE-974E-7DCC6A251124Q28539628-4C4EFAC3-ECC9-428B-AFF8-12B46B6CD532Q33160342-4B9BD0F3-96E9-4DE6-BEE4-4179A98C9290Q34615797-D9C5318D-4D9B-403D-8D09-0D532C1AE3FEQ35677270-0EEF83E6-8799-4006-8C6B-5EEBACA3F1DBQ35688489-49AD00DE-62AA-407E-8981-7FCA8C5881FDQ36675819-29F85E64-3F77-4704-A068-006C2CEDB615Q37038711-D6EAA2B7-7F10-42B2-9D03-9B6B74491667Q38110755-EE2675B3-9E7B-4098-B51F-07F455D83BC0Q43487048-FC2BB175-68BD-4C9C-B8A2-552255A65674Q48644420-E0BCB2B1-2828-46F1-86F7-8EC9623177F2
P2860
Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Multiple mechanisms of hERG li ...... poptosis induced by amoxapine.
@en
Multiple mechanisms of hERG li ...... poptosis induced by amoxapine.
@nl
type
label
Multiple mechanisms of hERG li ...... poptosis induced by amoxapine.
@en
Multiple mechanisms of hERG li ...... poptosis induced by amoxapine.
@nl
prefLabel
Multiple mechanisms of hERG li ...... poptosis induced by amoxapine.
@en
Multiple mechanisms of hERG li ...... poptosis induced by amoxapine.
@nl
P2093
P2860
P1476
Multiple mechanisms of hERG li ...... poptosis induced by amoxapine.
@en
P2093
Adrienne Dennis
Christoph A Karle
Dierk Thomas
Eckhard Ficker
Hande Erdal
Hugo A Katus
Ingo Staudacher
Jana Kisselbach
Patrick A Schweizer
Ramona Bloehs
P2860
P2888
P304
P356
10.1007/S00210-010-0496-7
P577
2010-03-13T00:00:00Z