Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice.

Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice.

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http://www.wikidata.org/entity/Q39729995
Activated Complement Factors as Disease Markers for SepsisDual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targetsPark7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsisCompstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention.Plasma Glycoproteomics Reveals Sepsis Outcomes Linked to Distinct Proteins in Common Pathways.Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunctionCombined Inhibition of Complement and CD14 Attenuates Bacteria-Induced Inflammation in Human Whole Blood More Efficiently Than Antagonizing the Toll-like Receptor 4-MD2 Complex.Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis.Human Endothelial Cell Activation by Escherichia coli and Staphylococcus aureus Is Mediated by TNF and IL-1β Secondarily to Activation of C5 and CD14 in Whole Blood.Early Diagnosis of Sepsis: Is an Integrated Omics Approach the Way Forward?The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load.Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis.Prognostic value of CD4(+)CD25(+) Tregs as a valuable biomarker for patients with sepsis in ICU.Complement C5-inhibitor rEV576 (coversin) ameliorates in-vivo effects of antiphospholipid antibodies.Thymulin, free or bound to PBCA nanoparticles, protects mice against chronic septic inflammation.Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization
P2860

Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice.

Item
http://www.wikidata.org/entity/Q39729995
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Double blockade of CD14 and co ...... polymicrobial sepsis in mice.
@en
Double blockade of CD14 and co ...... polymicrobial sepsis in mice.
@nl
type
label
Double blockade of CD14 and co ...... polymicrobial sepsis in mice.
@en
Double blockade of CD14 and co ...... polymicrobial sepsis in mice.
@nl
prefLabel
Double blockade of CD14 and co ...... polymicrobial sepsis in mice.
@en
Double blockade of CD14 and co ...... polymicrobial sepsis in mice.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Double blockade of CD14 and co ...... polymicrobial sepsis in mice.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932