Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma.
about
Full-length L1CAM and not its Δ2Δ27 splice variant promotes metastasis through induction of gelatinase expressionCombining antibody-directed presentation of IL-15 and 4-1BBL in a trifunctional fusion protein for cancer immunotherapy.L1 Cell Adhesion Molecule Promotes Migration and Invasion via JNK Activation in Extrahepatic Cholangiocarcinoma Cells with Activating KRAS Mutation.Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.L1CAM in human cancer.Antibody fragments directed against different portions of the human neural cell adhesion molecule L1 act as inhibitors or activators of L1 function.L1 cell adhesion molecule as a potential therapeutic target in murine models of endometriosis using a monoclonal antibody approach.L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer.Generation, characterization and preclinical studies of a human anti-L1CAM monoclonal antibody that cross-reacts with rodent L1CAMA chimeric antibody to L1 cell adhesion molecule shows therapeutic effect in an intrahepatic cholangiocarcinoma modelIdentification of differentially expressed genes according to chemosensitivity in advanced ovarian serous adenocarcinomas: expression of GRIA2 predicts better survival.Antibody targeting of CD24 efficiently retards growth and influences cytokine milieu in experimental carcinomasEvaluating L1CAM expression in human endometrial cancer using qRT-PCR.The Pleiotropic Role of L1CAM in Tumor VasculatureThe ubiquitous neural cell adhesion molecule (N-CAM).Molecular targets and pathways involved in liver metastasis of colorectal cancer.bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression.L1 cell adhesion molecule as a therapeutic target in cancer.Trastuzumab triggers phagocytic killing of high HER2 cancer cells in vitro and in vivo by interaction with Fcγ receptors on macrophages.Anti-L1CAM radioimmunotherapy is more effective with the radiolanthanide terbium-161 compared to lutetium-177 in an ovarian cancer model.L1CAM in the Early Enteric and Urogenital System.Influence of L1-CAM expression of breast cancer cells on adhesion to endothelial cells.CD24 controls Src/STAT3 activity in human tumors.CD24 promotes tumor cell invasion by suppressing tissue factor pathway inhibitor-2 (TFPI-2) in a c-Src-dependent fashion.Cetuximab may inhibit tumor growth and angiogenesis induced by ionizing radiation: a preclinical rationale for maintenance treatment after radiotherapyL1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1.Overexpression of L1CAM is associated with tumor progression and prognosis via ERK signaling in gastric cancer.L1CAM in early-stage type I endometrial cancer: results of a large multicenter evaluation.CHL1 Is Expressed and Functions as a Malignancy Promoter in Glioma Cells.L1 cell adhesion molecule (L1CAM) is a strong predictor for locoregional recurrences in cervical cancer.L1-CAM is commonly expressed in testicular germ cell tumours.
P2860
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P2860
Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Therapeutic antibodies to huma ...... e model for ovarian carcinoma.
@en
Therapeutic antibodies to huma ...... e model for ovarian carcinoma.
@nl
type
label
Therapeutic antibodies to huma ...... e model for ovarian carcinoma.
@en
Therapeutic antibodies to huma ...... e model for ovarian carcinoma.
@nl
prefLabel
Therapeutic antibodies to huma ...... e model for ovarian carcinoma.
@en
Therapeutic antibodies to huma ...... e model for ovarian carcinoma.
@nl
P2093
P1433
P1476
Therapeutic antibodies to huma ...... se model for ovarian carcinoma
@en
P2093
Gerhard Moldenhauer
Helena Kiefel
Jan Endell
Marco Pfeifer
Mina Fogel
Peter Altevogt
Sandra Lüttgau
Silke Wolterink
Ulrich Moebius
P304
P356
10.1158/0008-5472.CAN-09-3730
P407
P577
2010-03-09T00:00:00Z