Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption

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Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption

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Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption.

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Item

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Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption

@en

Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption.

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Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption

@en

Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption.

@nl

P1476

Minimizing Drug Exposure in the CNS while Maintaining Good Oral Absorption

@en

P2093

Peter J Bungay

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Sharan K Bagal

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P2860

A comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder.

Clinical pharmacokinetics of imatinib.

Full efficacy with no CNS side-effects: unachievable panacea or reality? DMPK considerations in design of drugs with limited brain penetration.

P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists.

Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug.

The influence of drug-like concepts on decision-making in medicinal chemistry.

Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors.

P304

948-950

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P31

scholarly article

editorial

P356

10.1021/ML300378N

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2012-11-15T00:00:00Z

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P5875

262886440

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P698

24900411

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P932

4025750

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