Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint. - Wikidata - awgldk - TriplyDB

Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint.

Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint.

http://www.wikidata.org/entity/Q39735633

about

Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1 Cyclin B1/Cdk1 binds and phosphorylates Filamin A and regulates its ability to cross-link actin Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction Bub1 regulates chromosome segregation in a kinetochore-independent manner Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint The spindle checkpoint requires cyclin-dependent kinase activity The spindle checkpoint and chromosome segregation in meiosis Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation Bub1-mediated adaptation of the spindle checkpoint Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis.The V260I mutation in fission yeast alpha-tubulin Atb2 affects microtubule dynamics and EB1-Mal3 localization and activates the Bub1 branch of the spindle checkpoint.Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation The nuclear kinase Lsk1p positively regulates the septation initiation network and promotes the successful completion of cytokinesis in response to perturbation of the actomyosin ring in Schizosaccharomyces pombe.Bub1 is a fission yeast kinetochore scaffold protein, and is sufficient to recruit other spindle checkpoint proteins to ectopic sites on chromosomes.The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function The spindle checkpoint, aneuploidy, and cancer.Optimization of the analogue-sensitive Cdc2/Cdk1 mutant by in vivo selection eliminates physiological limitations to its use in cell cycle analysis Genome-wide mapping of nuclear mitochondrial DNA sequences links DNA replication origins to chromosomal double-strand break formation in Schizosaccharomyces pombe.Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524.Spindle checkpoint activation at meiosis I advances anaphase II onset via meiosis-specific APC/C regulation Potential role of meiosis proteins in melanoma chromosomal instability Phosphorylation and activation of Bub1 on unattached chromosomes facilitate the spindle checkpoint.Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p.Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase.BUB1 and BUBR1: multifaceted kinases of the cell cycle.Bub1 and BubR1: at the interface between chromosome attachment and the spindle checkpoint Monitoring the fidelity of mitotic chromosome segregation by the spindle assembly checkpoint.Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores.The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase.Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling.The kinetochore protein Bub1 participates in the DNA damage response.Sli15(INCENP) dephosphorylation prevents mitotic checkpoint reengagement due to loss of tension at anaphase onset.Dual regulation of Mad2 localization on kinetochores by Bub1 and Dam1/DASH that ensure proper spindle interaction

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P2860

Function of Cdc2p-dependent Bub1p phosphorylation and Bub1p kinase activity in the mitotic and meiotic spindle checkpoint.

http://www.wikidata.org/entity/Q39735633

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-my

2003年学术文章

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2003年學術文章

@yue

2003年學術文章

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2003年學術文章

@zh-hant

name

Function of Cdc2p-dependent Bu ...... nd meiotic spindle checkpoint.

@en

Function of Cdc2p-dependent Bu ...... nd meiotic spindle checkpoint.

@nl

type

label

Function of Cdc2p-dependent Bu ...... nd meiotic spindle checkpoint.

@en

Function of Cdc2p-dependent Bu ...... nd meiotic spindle checkpoint.

@nl

prefLabel

Function of Cdc2p-dependent Bu ...... nd meiotic spindle checkpoint.

@en

Function of Cdc2p-dependent Bu ...... nd meiotic spindle checkpoint.

@nl

P1433

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P1433

The EMBO Journal

P1476

Function of Cdc2p-dependent Bu ...... nd meiotic spindle checkpoint.

@en

P2093

Anabelle Decottignies

http://www.w3.org/2001/XMLSchema#string

Paul Nurse

http://www.w3.org/2001/XMLSchema#string

Satoko Yamaguchi

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation of human MAD1 by the BUB1 kinase in vitro

Mutations of mitotic checkpoint genes in human cancers

The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function.

Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function.

Feedback control of mitosis in budding yeast

Differences in spindle association of the mitotic checkpoint protein Mad2 in mammalian spermatogenesis and oogenesis

P304

1075-1087

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scholarly article

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10.1093/EMBOJ/CDG100

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P407

P433

5

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P478

22

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P577

2003-03-01T00:00:00Z

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8133630

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P698

12606573

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phosphorylation

P932

150333

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