Ric-8B stabilizes the alpha subunit of stimulatory G protein by inhibiting its ubiquitination.
about
The G protein α chaperone Ric-8 as a potential therapeutic targetRic-8: different cellular roles for a heterotrimeric G-protein GEF.Implications of non-canonical G-protein signaling for the immune systemPurification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf).Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor.Increased ubiquitination and the crosstalk of G protein signaling in cardiac myocytes: involvement of Ric-8B in Gs suppression by Gq signal.The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1.RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassaGenetic variation in radiation-induced cell death.Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits.Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane associationRic-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα.Non-canonical signaling and localizations of heterotrimeric G proteins.Ric-8 regulation of heterotrimeric G proteins.The Ric-8B gene is highly expressed in proliferating preosteoblastic cells and downregulated during osteoblast differentiation in a SWI/SNF- and C/EBPbeta-mediated manner.Identification of a specific assembly of the g protein golf as a critical and regulated module of dopamine and adenosine-activated cAMP pathways in the striatum.G-Protein Dependent Signal Transduction and Ubiquitination in Dictyostelium.
P2860
Q26824363-9FA90585-893C-4751-AA81-E3013ABD8E67Q30415516-4F8A3183-F325-4588-995B-33832101054FQ33978840-7CAD6504-A0B3-4EB4-AB52-23D56D8439F6Q34509373-8683B8ED-FE6F-4769-B0FE-8DD5E920A0E7Q35011100-A7087931-A027-4339-A67C-EBAEEC488239Q35019673-12D9A1C3-CC7B-4405-A5E4-8BEB1E63C1B4Q35062664-2AD3CA31-7271-42A1-8AE3-322E010688E5Q35221553-86F3271C-630E-43C2-A3D3-7329793C0832Q35694405-35090F56-AC09-4203-90B1-081121FA1165Q36673368-6BF5CA9B-2353-40D0-9299-B9D05577EB95Q37408332-ECA29729-4411-489C-B41A-D1C9DB6C871CQ37530904-23485F31-0982-4CC1-B3C7-FB1A74AABEA8Q37930083-5D761441-DCC6-460E-99A9-BEBBA23DBBFEQ38079286-CACA926A-6000-4631-940F-70EA8A97D301Q39537696-BAD1E150-D10F-4533-AB20-8FA7E950D9DEQ42867430-55499B17-8E3F-4FFE-8259-52CB4CA2A0D2Q43789204-798EBA50-A046-4958-A73B-347199073703
P2860
Ric-8B stabilizes the alpha subunit of stimulatory G protein by inhibiting its ubiquitination.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Ric-8B stabilizes the alpha su ...... inhibiting its ubiquitination.
@en
Ric-8B stabilizes the alpha su ...... inhibiting its ubiquitination.
@nl
type
label
Ric-8B stabilizes the alpha su ...... inhibiting its ubiquitination.
@en
Ric-8B stabilizes the alpha su ...... inhibiting its ubiquitination.
@nl
prefLabel
Ric-8B stabilizes the alpha su ...... inhibiting its ubiquitination.
@en
Ric-8B stabilizes the alpha su ...... inhibiting its ubiquitination.
@nl
P2093
P2860
P356
P1476
Ric-8B stabilizes the alpha su ...... inhibiting its ubiquitination.
@en
P2093
Akiyuki Nishimura
Hiroshi Itoh
Kenji Tago
Norikazu Mizuno
Yusuke Nagai
P2860
P304
11114-11120
P356
10.1074/JBC.M109.063313
P407
P577
2010-02-04T00:00:00Z