Degradation of STAT1 and STAT2 by the V proteins of simian virus 5 and human parainfluenza virus type 2, respectively: consequences for virus replication in the presence of alpha/beta and gamma interferons.
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Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1Dengue virus inhibits alpha interferon signaling by reducing STAT2 expressionThe p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoterHepatitis B virus X protein and simian virus 5 V protein exhibit similar UV-DDB1 binding properties to mediate distinct activitiesViral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-AntagonistsPathogenesis of acute respiratory illness caused by human parainfluenza virusesThe C proteins of human parainfluenza virus type 1 block IFN signaling by binding and retaining Stat1 in perinuclear aggregates at the late endosomeStructural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 proteinVP8, the Major Tegument Protein of Bovine Herpesvirus 1, Interacts with Cellular STAT1 and Inhibits Interferon Beta SignalingInteraction of mumps virus V protein variants with STAT1-STAT2 heterodimer: experimental and theoretical studies.Human parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates.Mumps virus V protein antagonizes interferon without the complete degradation of STAT1.Growth restriction of an experimental live attenuated human parainfluenza virus type 2 vaccine in human ciliated airway epithelium in vitro parallels attenuation in African green monkeys.Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsivenessMapuera virus, a rubulavirus that inhibits interferon signalling in a wide variety of mammalian cells without degrading STATs.Identification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells.Human metapneumovirus inhibits IFN-β signaling by downregulating Jak1 and Tyk2 cellular levels.Recombinant human parainfluenza virus type 2 with mutations in V that permit cellular interferon signaling are not attenuated in non-human primates.Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion step.Human cytomegalovirus upregulates expression of the lectin galectin 9 via induction of beta interferonVirus replication in engineered human cells that do not respond to interferons.Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signalingTransient oscillatory dynamics of interferon beta signaling in macrophagesCharacterization of a potent refractory state and persistence of herpes simplex virus 1 in cell culture.Identification of human parainfluenza virus type 2 (HPIV-2) V protein amino acid residues that reduce binding of V to MDA5 and attenuate HPIV-2 replication in nonhuman primatesThe Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.Trypanosoma cruzi evades the protective role of interferon-gamma-signaling in parasite-infected cells.NS1 proteins of avian influenza A viruses can act as antagonists of the human alpha/beta interferon response.Mouse STAT2 restricts early dengue virus replicationInfection with the Persistent Murine Norovirus Strain MNV-S99 Suppresses IFN-Beta Release and Activation of Stat1 In Vitro.Role for the phosphoprotein P subunit of the paramyxovirus polymerase in limiting induction of host cell antiviral responsesSite-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs.Studies on the paramyxovirus accessory genes by reverse genetics in the Sendai virus-mouse system.The regulation of type I interferon production by paramyxoviruses.Conserved cysteine-rich domain of paramyxovirus simian virus 5 V protein plays an important role in blocking apoptosis.Paramyxovirus evasion of innate immunity: Diverse strategies for common targets.A novel anti-viral role for STAT3 in IFN-α signalling responses.Porcine Epidemic Diarrhea Virus Infection Inhibits Interferon Signaling by Targeted Degradation of STAT1.La Piedad Michoacán Mexico Virus V protein antagonizes type I interferon response by binding STAT2 protein and preventing STATs nuclear translocation
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P2860
Degradation of STAT1 and STAT2 by the V proteins of simian virus 5 and human parainfluenza virus type 2, respectively: consequences for virus replication in the presence of alpha/beta and gamma interferons.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Degradation of STAT1 and STAT2 ...... ha/beta and gamma interferons.
@en
Degradation of STAT1 and STAT2 ...... ha/beta and gamma interferons.
@nl
type
label
Degradation of STAT1 and STAT2 ...... ha/beta and gamma interferons.
@en
Degradation of STAT1 and STAT2 ...... ha/beta and gamma interferons.
@nl
prefLabel
Degradation of STAT1 and STAT2 ...... ha/beta and gamma interferons.
@en
Degradation of STAT1 and STAT2 ...... ha/beta and gamma interferons.
@nl
P2093
P2860
P1433
P1476
Degradation of STAT1 and STAT2 ...... ha/beta and gamma interferons.
@en
P2093
J Andrejeva
R E Randall
S Goodbourn
P2860
P304
P356
10.1128/JVI.76.5.2159-2167.2002
P407
P577
2002-03-01T00:00:00Z