CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa. - Wikidata - awgldk - TriplyDB

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

http://www.wikidata.org/entity/Q39749802

about

Unexpected mutations after CRISPR–Cas9 editing in vivo CRISPR-Cas Genome Surgery in Ophthalmology.Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes.Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration.In vivo versus ex vivo CRISPR therapies for retinal dystrophy.Insights from Genetic Model Systems of Retinal Degeneration: Role of Epsins in Retinal Angiogenesis and VEGFR2 Signaling.Correction of Monogenic and Common Retinal Disorders with Gene Therapy.CRISPR applications in ophthalmologic genome surgery.Cell-based therapeutic strategies for replacement and preservation in retinal degenerative diseases.Delivery technologies for genome editing.Applications of CRISPR/Cas9 in retinal degenerative diseases Gene therapy approaches for prevention of retinal degeneration in Usher syndrome.Repair of the TGFBI gene in human corneal keratocytes derived from a granular corneal dystrophy patient via CRISPR/Cas9-induced homology-directed repair.CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa: A Brief Methodology.CRISPR-mediated Ophthalmic Genome Surgery.CRISPR in the Retina: Evaluation of Future Potential.Glioblastoma: new therapeutic strategies to address cellular and genomic complexity.Genome Surgery and Gene Therapy in Retinal Disorders.Gene therapy and genome surgery in the retina.Guiding Lights in Genome Editing for Inherited Retinal Disorders: Implications for Gene and Cell Therapy.Low incidence of SNVs and indels in trio genomes of Cas9-mediated multiplex edited sheep.Translation of CRISPR Genome Surgery to the Bedside for Retinal Diseases.CRISPR/Cas9 genome surgery for retinal diseases In Vivo Genome Editing as a Therapeutic Approach

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CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

http://www.wikidata.org/entity/Q39749802

description

2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

@zh-my

2016年学术文章

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2016年學術文章

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2016年學術文章

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2016年學術文章

@zh-hant

name

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

@en

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

@nl

type

label

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

@en

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

@nl

prefLabel

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

@en

CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

@nl

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Molecular Therapy

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CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

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P2093

Alexander G Bassuk

http://www.w3.org/2001/XMLSchema#string

Chyuan-Sheng Lin

http://www.w3.org/2001/XMLSchema#string

Lijuan Zhang

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Sally Justus

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Stephen H Tsang

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Ting-Ting Lee

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Vinit B Mahajan

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Wen-Hsuan Wu

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Yi-Ting Tsai

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P2860

Mutation spectrum of the gene encoding the beta subunit of rod phosphodiesterase among patients with autosomal recessive retinitis pigmentosa

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes

Multiplex genome engineering using CRISPR/Cas systems

THE GEOTROPIC REACTION OF RODLESS MICE IN LIGHT AND IN DARKNESS

Retinitis pigmentosa

Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase.

Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines.

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa

Halting progressive neurodegeneration in advanced retinitis pigmentosa

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1388-1394

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scholarly article

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10.1038/MT.2016.107

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8

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24

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27203441

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