Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice - Wikidata - awgldk - TriplyDB

Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice

Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice

http://www.wikidata.org/entity/Q39750347

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Signaling by STATs Androgen receptor (AR) in cardiovascular diseases The Complex Role of STAT3 in Viral Infections Signal transducer and activator of transcription 3 (STAT3) protein suppresses adenoma-to-carcinoma transition in Apcmin/+ mice via regulation of Snail-1 (SNAI) protein stability NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses Inflammatory bowel disease The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model?Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models.Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.Toll-like receptors in inflammatory bowel diseases: a decade later.Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2 Dendritic cell (DC)-specific targeting reveals Stat3 as a negative regulator of DC function.Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance.A distal enhancer in Il12b is the target of transcriptional repression by the STAT3 pathway and requires the basic leucine zipper (B-ZIP) protein NFIL3.The microbiome in infectious disease and inflammation.Stat3: friend or foe in colitis and colitis-associated cancer?Experimental Models of Inflammatory Bowel Diseases.Negative regulation of Toll-like receptor signaling plays an essential role in homeostasis of the intestine.The fundamental basis of inflammatory bowel disease.Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice Functions of innate immune cells and commensal bacteria in gut homeostasis.Intestinal CX3C chemokine receptor 1(high) (CX3CR1(high)) myeloid cells prevent T-cell-dependent colitis.Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon Innate pathways to B-cell activation and tolerance.Maintenance of gut homeostasis by the mucosal immune system.Endothelial cells require STAT3 for protection against endotoxin-induced inflammation MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice STAT3: a potential therapeutic target in dendritic cells for the induction of transplant tolerance.Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis.The straw that stirs the drink: insight into the pathogenesis of inflammatory bowel disease revealed through the study of microflora-induced inflammation in genetically modified mice.Interleukin-35 mediates mucosal immune responses that protect against T-cell-dependent colitis.Bacterial-mucosal interactions in inflammatory bowel disease: an alliance gone bad Gut microflora: a new target for therapeutic approaches in inflammatory bowel disease.Dendritic cells in intestinal immune regulation.The Fasciola hepatica tegumental antigen suppresses dendritic cell maturation and function.STAT3 regulates proliferation and survival of CD8+ T cells: enhances effector responses to HSV-1 infection, and inhibits IL-10+ regulatory CD8+ T cells in autoimmune uveitis.Genetic susceptibility to allergic bronchopulmonary aspergillosis in asthma: a genetic association study

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P2860

Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice

http://www.wikidata.org/entity/Q39750347

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2003 nî lūn-bûn

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2003年學術文章

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name

Toll-like receptor-dependent p ...... -specific Stat3-deficient mice

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Toll-like receptor-dependent p ...... specific Stat3-deficient mice.

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type

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Toll-like receptor-dependent p ...... -specific Stat3-deficient mice

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Toll-like receptor-dependent p ...... specific Stat3-deficient mice.

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Toll-like receptor-dependent p ...... -specific Stat3-deficient mice

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Toll-like receptor-dependent p ...... specific Stat3-deficient mice.

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Journal of Clinical Investigation

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Toll-like receptor-dependent p ...... -specific Stat3-deficient mice

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Hiroshi Kiyono

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Hirotaka Kuwata

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Kiyoshi Takeda

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Masaya Kobayashi

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Mi-Na Kweon

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Robert D Schreiber

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P2860

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

A Toll-like receptor recognizes bacterial DNA

Interleukin-10 and the interleukin-10 receptor

Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

Innate immune recognition

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

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12727921

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Toll-like receptor

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154445

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