Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. - Wikidata - awgldk - TriplyDB

Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity.

Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity.

http://www.wikidata.org/entity/Q39754221

about

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1 A nucleolar protein RRS1 contributes to chromosome congression Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly Regulation of the centrosome cycle Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin Uncoordinated loss of chromatid cohesion is a common outcome of extended metaphase arrest Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication Possible functional links among brain- and skull-related genes selected in modern humans Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation.Oscillation of APC/C activity during cell cycle arrest promotes centrosome amplification.Kinetochore-microtubule stability governs the metaphase requirement for Eg5.Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion.A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.Interplay of microtubule dynamics and sliding during bipolar spindle formation in mammalian cells SPAG5 upregulation predicts poor prognosis in cervical cancer patients and alters sensitivity to taxol treatment via the mTOR signaling pathway.The multifunctional SNM1 gene family: not just nucleases Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores.A centrosome-autonomous signal that involves centriole disengagement permits centrosome duplication in G2 phase after DNA damage.CENP-W plays a role in maintaining bipolar spindle structure.Centrosome dynamics as a source of chromosomal instability Sensors at centrosomes reveal determinants of local separase activity.Is cohesin required for spindle-pole-body/centrosome cohesion?STIL binding to Polo-box 3 of PLK4 regulates centriole duplication Kizuna is a novel mitotic substrate for CDC25B phosphatase Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole integrity.Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules.3D-structured illumination microscopy provides novel insight into architecture of human centrosomes.The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division.The mitotic spindle protein SPAG5/Astrin connects to the Usher protein network postmitotically Structural and regulatory roles of nonmotor spindle proteins miR-539 inhibits prostate cancer progression by directly targeting SPAG5 Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres Centrioles: some self-assembly required.Identification of novel small molecule inhibitors of centrosome clustering in cancer cells Mechanisms of Chromosome Congression during Mitosis.

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P2860

Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity.

http://www.wikidata.org/entity/Q39754221

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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name

Astrin is required for the mai ...... sion and centrosome integrity.

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Astrin is required for the mai ...... sion and centrosome integrity.

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type

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Astrin is required for the mai ...... sion and centrosome integrity.

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Astrin is required for the mai ...... sion and centrosome integrity.

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Astrin is required for the mai ...... sion and centrosome integrity.

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Astrin is required for the mai ...... sion and centrosome integrity.

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P1433

Journal of Cell Biology

P1476

Astrin is required for the mai ...... sion and centrosome integrity.

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P2093

Julia Kleylein-Sohn

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Kerstin H Thein

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Ulrike Gruneberg

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P2860

Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells

Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

CENP-E is a putative kinetochore motor that accumulates just before mitosis

TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly

Regulation of human separase by securin binding and autocleavage

Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2

Analysis of mitotic microtubule-associated proteins using mass spectrometry identifies astrin, a spindle-associated protein

Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay

The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells

hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells

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345-354

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10.1083/JCB.200701163

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3

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178

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17664331

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2064855

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