Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility - Wikidata - awgldk - TriplyDB

Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility

Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility

http://www.wikidata.org/entity/Q39756940

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Aerosols transmit prions to immunocompetent and immunodeficient mice The diverse roles of mononuclear phagocytes in prion disease pathogenesis Prion uptake in the gut: identification of the first uptake and replication sites Biochemical properties of highly neuroinvasive prion strains Scrapie affects the maturation cycle and immune complex trapping by follicular dendritic cells in mice PRNP promoter polymorphisms are associated with BSE susceptibility in Swiss and German cattle Paracrine diffusion of PrP(C) and propagation of prion infectivity by plasma membrane-derived microvesicles Repetitive immunization enhances the susceptibility of mice to peripherally administered prions.Bacterial colitis increases susceptibility to oral prion disease.Application of "omics" to prion biomarker discovery.Pathogenesis of chronic wasting disease in cervidized transgenic mice.Extraneural prion neuroinvasion without lymphoreticular system infection.Chronic wasting disease.Role of lymphotoxin in experimental models of infectious diseases: potential benefits and risks of a therapeutic inhibition of the lymphotoxin-beta receptor pathway.Co-infection with the friend retrovirus and mouse scrapie does not alter prion disease pathogenesis in susceptible mice.Resistance of neonatal mice to scrapie is associated with inefficient infection of the immature spleen.Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes.Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infection Immunization with recombinant prion protein leads to partial protection in a murine model of TSEs through a novel mechanism Strain fidelity of chronic wasting disease upon murine adaptation.Molecular neurology of prion disease.The effects of host age on the transport of complement-bound complexes to the spleen and the pathogenesis of intravenous scrapie infection.Oral delivery of pathogens from the intestine to the nervous system.Antiprion immunotherapy: to suppress or to stimulate?Rational targeting for prion therapeutics.B cell-specific S1PR1 deficiency blocks prion dissemination between secondary lymphoid organs Progress in prion vaccines and immunotherapies.Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility Prions and their lethal journey to the brain.Prion diseases of humans and farm animals: epidemiology, genetics, and pathogenesis.The spread of prions through the body in naturally acquired transmissible spongiform encephalopathies.Role of CD40 in prion disease and the immune response to recombinant PrP A role for B lymphocytes in anti-infective prion therapies?Tunnelling nanotubes: a highway for prion spreading?Complement protein C3 exacerbates prion disease in a mouse model of chronic wasting disease.Cells and prions: a license to replicate.Therapeutic interventions ameliorating prion disease.Immunotherapeutic approaches in prion disease: progress, challenges and potential directions.Determining the role of mononuclear phagocytes in prion neuroinvasion from the skin.Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells.

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P2860

Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility

http://www.wikidata.org/entity/Q39756940

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Follicular dendritic cell dedi ...... reduces scrapie susceptibility

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Follicular dendritic cell dedi ...... educes scrapie susceptibility.

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Follicular dendritic cell dedi ...... reduces scrapie susceptibility

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Follicular dendritic cell dedi ...... educes scrapie susceptibility.

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Follicular dendritic cell dedi ...... reduces scrapie susceptibility

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Follicular dendritic cell dedi ...... educes scrapie susceptibility.

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Journal of Virology

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Follicular dendritic cell dedi ...... reduces scrapie susceptibility

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Irene McConnell

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Janice Young

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Moira E Bruce

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P2860

Impaired prion replication in spleens of mice lacking functional follicular dendritic cells

Follicular dendritic cells, interdigitating cells, and cells of the monocyte-macrophage lineage are the C1q-producing sources in the spleen. Identification of specific cell types by in situ hybridization and immunohistochemical analysis

Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice

Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells

The role of complement in the acquired immune response.

Accumulation of prion protein in tonsil and appendix: review of tissue samples

Drug and gene targeting to the brain with molecular Trojan horses.

Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway

Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie.

Prion protein expression in different species: analysis with a panel of new mAbs

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