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Tumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?Humans accumulate microsatellite instability with acquired loss of MLH1 protein in hematopoietic stem and progenitor cells as a function of ageDNA methyltransferases, DNA damage repair, and cancerMSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells.Functional analysis in mouse embryonic stem cells reveals wild-type activity for three MSH6 variants found in suspected Lynch syndrome patients.Agenesis of the corpus callosum and gray matter heterotopia in three patients with constitutional mismatch repair deficiency syndrome.DNA methylation and cancer diagnosis.Assessing how reduced expression levels of the mismatch repair genes MLH1, MSH2, and MSH6 affect repair efficiency.Mismatch repair analysis of inherited MSH2 and/or MSH6 variation pairs found in cancer patients.Loss of MSH2 and MSH6 due to heterozygous germline defects in MSH3 and MSH6.Inflammation-associated microsatellite alterations: Mechanisms and significance in the prognosis of patients with colorectal cancer.MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loopMSH2:MSH3 binds insertion/deletion loop of 2 bases or moreHuman DNA polymerase α interacts with mismatch repair proteins MSH2 and MSH6.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
MutSbeta exceeds MutSalpha in dinucleotide loop repair.
@en
MutSbeta exceeds MutSalpha in dinucleotide loop repair.
@nl
type
label
MutSbeta exceeds MutSalpha in dinucleotide loop repair.
@en
MutSbeta exceeds MutSalpha in dinucleotide loop repair.
@nl
prefLabel
MutSbeta exceeds MutSalpha in dinucleotide loop repair.
@en
MutSbeta exceeds MutSalpha in dinucleotide loop repair.
@nl
P2093
P2860
P356
P1476
MutSbeta exceeds MutSalpha in dinucleotide loop repair.
@en
P2093
J Kantelinen
K Heinimann
M K Korhonen
M Kansikas
P2860
P2888
P304
P356
10.1038/SJ.BJC.6605531
P407
P577
2010-02-16T00:00:00Z
P5875
P6179
1028241908