Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis. - Wikidata - awgldk - TriplyDB

Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis.

Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis.

http://www.wikidata.org/entity/Q39765865

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Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy Prostaglandins and cancer Up-regulation of prostaglandin E receptor EP2 and EP4 subtypes in rat synovial tissues with adjuvant arthritis Pathophysiology of vascular dysfunction in a rat model of chronic joint inflammation.Discovery of a novel activator of 5-lipoxygenase from an anacardic acid derived compound collection.Prostanoid receptor EP2 as a therapeutic target Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and the risk of colorectal adenoma.Basic biology and clinical application of specific cyclooxygenase-2 inhibitors.Not a mouse stirring: deletion of the EP2 and love's labor's lost Signal transduction in esophageal and LES circular muscle contraction Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-kappaB activation.Cholera toxin B subunit activates arachidonic acid metabolism Shear-induced interleukin-6 synthesis in chondrocytes: roles of E prostanoid (EP) 2 and EP3 in cAMP/protein kinase A- and PI3-K/Akt-dependent NF-kappaB activation.Interleukin-6 synthesis in human chondrocytes is regulated via the antagonistic actions of prostaglandin (PG)E2 and 15-deoxy-Δ(12,14)-PGJ2.COX-2 and Alzheimer's disease: potential roles in inflammation and neurodegeneration.Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases The development of COX2 inhibitors.Therapeutic potential of COX-2 inhibitors in arthritis.Suppression of adipogenesis by pathogenic seipin mutant is associated with inflammatory response The cycloxygenase 2 (COX-2) story: it's time to explain, not inflame.Comparison of Anti-inflammatory Activities of Six Curcuma Rhizomes: A Possible Curcuminoid-independent Pathway Mediated by Curcuma phaeocaulis Extract.Cyclooxygenase-2 inhibitors: promise or peril?Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis Calcineurin inhibitors exert rapid reduction of inflammatory pain in rat adjuvant-induced arthritis.Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2.Prostaglandin E2 induces fibroblast growth factor 9 via EP3-dependent protein kinase Cdelta and Elk-1 signaling.Concept, mechanisms and therapeutics of angiogenesis in cancer and other diseases.Topically applied phospho-sulindac hydrogel is efficacious and safe in the treatment of experimental arthritis in rats.Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model Long term NSAID treatment inhibits COX-2 synthesis in the knee synovial membrane of patients with osteoarthritis: differential proinflammatory cytokine profile between celecoxib and aceclofenac Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E2 Calotropis procera latex extract affords protection against inflammation and oxidative stress in Freund's complete adjuvant-induced monoarthritis in rats.Role of COX-2 inhibitors in cancer therapy.Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma Anti-inflammatory and anti-arthritic activity of a methanol extract from Vitellaria paradoxa stem bark.Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo.Mitigation of Inflammation-Induced Mood Dysregulation by Long-Chain Omega-3 Fatty Acids PGE2 EP1 receptor deletion attenuates 6-OHDA-induced Parkinsonism in mice: old switch, new target.Elevated immune-inflammatory signaling in mood disorders: a new therapeutic target?Pharmacological analysis of cyclooxygenase-1 in inflammation

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P2860

Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis.

http://www.wikidata.org/entity/Q39765865

description

1996 nî lūn-bûn

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1996年の論文

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年學術文章

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1996年學術文章

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1996年學術文章

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name

Selective inhibition of cycloo ...... n 6 in rat adjuvant arthritis.

@en

Selective inhibition of cyclooxygenase

@nl

type

label

Selective inhibition of cycloo ...... n 6 in rat adjuvant arthritis.

@en

Selective inhibition of cyclooxygenase

@nl

prefLabel

Selective inhibition of cycloo ...... n 6 in rat adjuvant arthritis.

@en

Selective inhibition of cyclooxygenase

@nl

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Journal of Clinical Investigation

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Selective inhibition of cycloo ...... n 6 in rat adjuvant arthritis.

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Anderson GD

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Bremer ME

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Gregory SA

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Hauser SD

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Isakson PC

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McGarity KL

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P2860

Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues

Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases

Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes.

Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.

Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase.

Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice.

Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis.

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.

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10.1172/JCI118717

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