Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides

Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides

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http://www.wikidata.org/entity/Q39766098
Engineering biodegradable and multifunctional peptide-based polymers for gene delivery.Separation of polyethylene glycols and maleimide-terminated polyethylene glycols by reversed-phase liquid chromatography under critical conditions.Miniaturization of gene transfection assays in 384- and 1536-well microplates.Peptides, polypeptides and peptide-polymer hybrids as nucleic acid carriers.Discovery of metabolically stabilized electronegative polyacridine-PEG peptide DNA open polyplexes.N-glycan targeted gene delivery to the dendritic cell SIGN receptor.High-affinity PEGylated polyacridine peptide polyplexes mediate potent in vivo gene expression.Metabolically stabilized long-circulating PEGylated polyacridine peptide polyplexes mediate hydrodynamically stimulated gene expression in liver.PEG length and chemical linkage controls polyacridine peptide DNA polyplex pharmacokinetics, biodistribution, metabolic stability and in vivo gene expression.A Convergent Synthesis of Homogeneous Reducible Polypeptides.Dual secured nano-melittin for the safe and effective eradication of cancer cells.Efficient expression of stabilized mRNA PEG-peptide polyplexes in liver.Solid-phase supported design of carriers for therapeutic nucleic acid delivery.Exploring the mechanism of plasmid DNA nuclear internalization with polymer-based vehicles.
P2860

Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides

Item
http://www.wikidata.org/entity/Q39766098
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides
@en
Synthesis and in vitro testing ...... littin gene delivery peptides.
@nl
type
label
Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides
@en
Synthesis and in vitro testing ...... littin gene delivery peptides.
@nl
prefLabel
Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides
@en
Synthesis and in vitro testing ...... littin gene delivery peptides.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Synthesis and in vitro testing of new potent polyacridine-melittin gene delivery peptides
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932