Detergent-Mediated Formation of β-Hematin: Heme Crystallization Promoted by Detergents Implicates Nanostructure Formation for Use as a Biological Mimic.

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Deconstructing Quinoline-Class Antimalarials to Identify Fundamental Physicochemical Properties of Beta-Hematin Crystal Growth Inhibitors.High-Content Screening of MMV Pathogen Box for Plasmodium falciparum Digestive Vacuole Disrupting Molecules Reveals Valuable Starting Points for Drug Discovery.

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P2860

Detergent-Mediated Formation of β-Hematin: Heme Crystallization Promoted by Detergents Implicates Nanostructure Formation for Use as a Biological Mimic.

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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Detergent-Mediated Formation o ...... for Use as a Biological Mimic.

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Detergent-Mediated Formation o ...... for Use as a Biological Mimic.

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Detergent-Mediated Formation o ...... for Use as a Biological Mimic.

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Detergent-Mediated Formation o ...... for Use as a Biological Mimic.

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Detergent-Mediated Formation o ...... for Use as a Biological Mimic.

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Detergent-Mediated Formation o ...... for Use as a Biological Mimic.

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Detergent-Mediated Formation o ...... for Use as a Biological Mimic.

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P2093

Christopher P Gulka

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David W Wright

http://www.w3.org/2001/XMLSchema#string

Jenny E Nesbitt

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Kim Y Fong

http://www.w3.org/2001/XMLSchema#string

Matheus P Oliveira

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Rebecca D Sandlin

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Renata Stiebler

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P2860

Phospholipid membrane-mediated hemozoin formation: the effects of physical properties and evidence of membrane surrounding hemozoin

Hemozoin and antimalarial drug discovery

Identification of β-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity.

The neutral lipid composition present in the digestive vacuole of Plasmodium falciparum concentrates heme and mediates β-hematin formation with an unusually low activation energy.

Speciation and structure of ferriprotoporphyrin IX in aqueous solution: spectroscopic and diffusion measurements demonstrate dimerization, but not mu-oxo dimer formation.

Food vacuole-associated lipid bodies and heterogeneous lipid environments in the malaria parasite, Plasmodium falciparum.

Increase on the initial soluble heme levels in acidic conditions is an important mechanism for spontaneous heme crystallization in vitro

The structure of malaria pigment beta-haematin.

Haemozoin in Schistosoma mansoni.

Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles.

P304

2542-2551

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scholarly article

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10.1021/ACS.CGD.5B01580

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Marcus Fernandes Oliveira

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2016-04-11T00:00:00Z

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27175104

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4860678

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Detergent-Mediated Formation of β-Hematin: Heme Crystallization Promoted by Detergents Implicates Nanostructure Formation for Use as a Biological Mimic.

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P2860

P2860

Detergent-Mediated Formation of β-Hematin: Heme Crystallization Promoted by Detergents Implicates Nanostructure Formation for Use as a Biological Mimic.

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