Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
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Centrosome - a promising anti-cancer targetCyclin D as a therapeutic target in cancerUSP9X regulates centrosome duplication and promotes breast carcinogenesis.E2F activators signal and maintain centrosome amplification in breast cancer cells.The centriole duplication cycle.Resveratrol inhibits proliferation in human colorectal carcinoma cells by inducing G1/S‑phase cell cycle arrest and apoptosis through caspase/cyclin‑CDK pathways.The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells.The G1 phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification.Cdk4 and nek2 signal binucleation and centrosome amplification in a her2+ breast cancer model.Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts.RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts.Cytoplasmic nucleophosmin has elevated T199 phosphorylation upon which G2/M phase progression is dependent.Aging and Loss of Circulating 17β-Estradiol Alters the Alternative Splicing of ERβ in the Female Rat Brain.Cyclin-Dependent Kinase Inhibitors as Anticancer TherapeuticsInteractions of the natural product (+)-avrainvillamide with nucleophosmin and exportin-1 Mediate the cellular localization of nucleophosmin and its AML-associated mutants.Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints.Targeting NEK2 as a promising therapeutic approach for cancer treatment.14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression.Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis.Opposing post-translational modifications regulate Cep76 function to suppress centriole amplification.Nucleolar proteomics and viral infection.Such small hands: the roles of centrins/caltractins in the centriole and in genome maintenance.Regulation of the g1/s transition in hepatocytes: involvement of the cyclin-dependent kinase cdk1 in the DNA replication.RB1 in cancer: different mechanisms of RB1 inactivation and alterations of pRb pathway in tumorigenesis.Ubiquitin, the centrosome, and chromosome segregation.Immortalization of human normal and NF1 neurofibroma Schwann cells.Genome Stability Requires p53.AP4 is required for mitogen- and c-MYC-induced cell cycle progression.Screening on human hepatoma cell line HepG-2 nucleus and cytoplasm protein after CDK2 silencing by RNAi.Alternol induces an S-phase arrest of melanoma B16F0 cells.The Role of Aneuploidy in Cancer Evolution.The involvement of MCT-1 oncoprotein in inducing mitotic catastrophe and nuclear abnormalities.Alteronol inhibits proliferation in HeLa cells through inducing a G1-phase arrest.Isoliquiritigenin induces apoptosis of human bladder cancer T24 cells via a cyclin-dependent kinase-independent mechanismIkk2 regulates cytokinesis during vertebrate development.AIRE is a critical spindle-associated protein in embryonic stem cells.CUEDC2 down-regulation is associated with tumor growth and poor prognosis in lung adenocarcinoma.The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1.Building the right centriole for each cell type.
P2860
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P2860
Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
@zh-hant
name
Cdk2 and Cdk4 regulate the cen ...... plification in p53-null cells.
@en
Cdk2 and Cdk4 regulate the cen ...... plification in p53-null cells.
@nl
type
label
Cdk2 and Cdk4 regulate the cen ...... plification in p53-null cells.
@en
Cdk2 and Cdk4 regulate the cen ...... plification in p53-null cells.
@nl
prefLabel
Cdk2 and Cdk4 regulate the cen ...... plification in p53-null cells.
@en
Cdk2 and Cdk4 regulate the cen ...... plification in p53-null cells.
@nl
P2093
P2860
P356
P1476
Cdk2 and Cdk4 regulate the cen ...... mplification in p53-null cells
@en
P2093
Arsene M Adon
Harold I Saavedra
Hiroaki Kiyokawa
Mary K Harrison
Stacy Sannem
Xiangbin Zeng
P2860
P304
P356
10.1128/MCB.00253-09
P407
P577
2009-11-23T00:00:00Z