Regulation of mitophagy by the Gp78 E3 ubiquitin ligase. - Wikidata - awgldk - TriplyDB

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

http://www.wikidata.org/entity/Q39774003

about

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin Mitochondrial Dysfunction in Alzheimer's Disease and the Rationale for Bioenergetics Based Therapies Mitochondrial quality control: decommissioning power plants in neurodegenerative diseases Autophagosome dynamics in neurodegeneration at a glance PMI: a ΔΨm independent pharmacological regulator of mitophagy Mitophagy: Basic Mechanism and Potential Role in Kidney Diseases New method to assess mitophagy flux by flow cytometry Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients An ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion.Keeping the immune system in check: a role for mitophagy.Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD A53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways.p38 MAP kinase-dependent phosphorylation of the Gp78 E3 ubiquitin ligase controls ER-mitochondria association and mitochondria motility NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1.Characterization of the cardiac succinylome and its role in ischemia-reperfusion injury.Regulation of mitochondrial antiviral signaling (MAVS) expression and signaling by the mitochondria-associated endoplasmic reticulum membrane (MAM) protein Gp78.Dynamic survey of mitochondria by ubiquitin.Mitochondrial autophagy--an essential quality control mechanism for myocardial homeostasis.Mitophagy.Autophagy coupling interplay: can improve cellular repair and aging?Organellophagy: eliminating cellular building blocks via selective autophagy.ERAD and how viruses exploit it.Regulation of autophagy by protein post-translational modification.Emerging role of selective autophagy in human diseases.Radiation-induced autophagy: mechanisms and consequences.Complex formation and turnover of mitochondrial transporters and ion channels.Mitochondrial dysfunction in inflammatory responses and cellular senescence: pathogenesis and pharmacological targets for chronic lung diseases.Parkin and mitophagy in cancer.PERM Hypothesis: The Fundamental Machinery Able to Elucidate the Role of Xenobiotics and Hormesis in Cell Survival and Homeostasis The pharmacological regulation of cellular mitophagy.Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy.Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis.Commentary: Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson's disease.CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling.Methods for Mitochondria and Mitophagy Flux Analyses in Stem Cells of Resting and Regenerating Skeletal Muscle.Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy.Clec16a, Nrdp1, and USP8 Form a Ubiquitin-Dependent Tripartite Complex That Regulates β-Cell Mitophagy.

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P2860

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

http://www.wikidata.org/entity/Q39774003

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh

2013年學術文章

@zh-hant

name

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

@en

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

@nl

type

label

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

@en

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

@nl

prefLabel

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

@en

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

@nl

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P356

MBC.E12-08-0607

P1433

Molecular Biology of the Cell

P1476

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

@en

P2093

Bharat Joshi

http://www.w3.org/2001/XMLSchema#string

Ivan R Nabi

http://www.w3.org/2001/XMLSchema#string

Jay Shankar

http://www.w3.org/2001/XMLSchema#string

Min Fu

http://www.w3.org/2001/XMLSchema#string

Pascal St-Pierre

http://www.w3.org/2001/XMLSchema#string

Peter T C Wang

http://www.w3.org/2001/XMLSchema#string

P2860

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

OPA1 requires mitofusin 1 to promote mitochondrial fusion

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1153-1162

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scholarly article

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10.1091/MBC.E12-08-0607

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8

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24

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2013-02-20T00:00:00Z

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235682832

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23427266

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3623636

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