Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

about

Effect of N-methyl deuteration on metabolism and pharmacokinetics of enzalutamide.Design, synthesis and biological evaluation of deuterated nintedanib for improving pharmacokinetic properties.

P2860

Q37082790-27329B4B-46BD-4D8C-BF61-E2972D253326 Q53215838-EDD7D4FA-0EE3-45DC-BB18-7F52867EDBC8

P2860

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

Item

http://www.wikidata.org/entity/Q39781068

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

@en

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

@nl

type

Item

label

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

@en

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

@nl

prefLabel

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

@en

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

@nl

P1476

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

@en

P2093

Bo Jiao

http://www.w3.org/2001/XMLSchema#string

Yaoqiu Zhu

http://www.w3.org/2001/XMLSchema#string

P2860

Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis

Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events

Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity

Structure and stereochemistry of the active metabolite of clopidogrel.

The resurgence of covalent drugs.

Mechanism-based inactivation of human cytochrome P450 2B6 by clopidogrel: involvement of both covalent modification of cysteinyl residue 475 and loss of heme

Overcoming 'resistance' to antiplatelet therapy: targeting the issue of nonadherence.

In vitro biotransformation studies of 2-oxo-clopidogrel: multiple thiolactone ring-opening pathways further attenuate prodrug activation.

Identification of the Significant Involvement and Mechanistic Role of CYP3A4/5 in Clopidogrel Bioactivation

Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.

P304

349-352

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/ML300460T

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Jiang Zhou

P577

2013-02-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

24900671

http://www.w3.org/2001/XMLSchema#string

P921

clopidogrel

P932

4027567

http://www.w3.org/2001/XMLSchema#string

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

about

P2860

P2860

Deuterated clopidogrel analogues as a new generation of antiplatelet agents.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932