Rituximab-mediated cell signaling and chemo/immuno-sensitization of drug-resistant B-NHL is independent of its Fc functions.
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Rituximab: mechanism of actionChronic Lymphocytic Leukemia: Exploiting Vulnerabilities with Targeted AgentsBone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistanceMechanisms of action of therapeutic antibodies for cancerTumor microenvironment and immune effects of antineoplastic therapy in lymphoproliferative syndromes.Rituximab resistance.Expanding the targets available to therapeutic antibodies via novel disease-specific markers.Transcription regulator Yin-yang 1: from silence to cancer.Scientific rationale for extrapolation of biosimilar data across cancer indications: case study of CT-P10.Overcoming rituximab drug-resistance by the genetically engineered anti-CD20-hIFN-α fusion protein: Direct cytotoxicity and synergy with chemotherapy.Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers.The role of cytokines in the regulation of drug disposition: extended functional pleiotropism?Rituximab: as first-line maintenance therapy following rituximab-containing therapy for follicular lymphoma.Postulated mechanisms of resistance of B-cell non-Hodgkin lymphoma to rituximab treatment regimens: strategies to overcome resistance.Rituximab: modes of action, remaining dispute and future perspective.RKIP-mediated chemo-immunosensitization of resistant cancer cells via disruption of the NF-κB/Snail/YY1/RKIP resistance-driver loopExpression of KLF4 is a predictive marker for survival in pediatric Burkitt lymphoma.Novel humanized anti-CD20 antibody BM-ca binds to a unique epitope and exerts stronger cellular activity than others.TGF-β-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD20.Aurora A inhibitor (MLN8237) plus vincristine plus rituximab is synthetic lethal and a potential curative therapy in aggressive B-cell non-Hodgkin lymphoma.Mcl-1 and YY1 inhibition and induction of DR5 by the BH3-mimetic Obatoclax (GX15-070) contribute in the sensitization of B-NHL cells to TRAIL apoptosis.A comparative global phosphoproteomics analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment.Drug-Free Macromolecular Therapeutics Induce Apoptosis via Calcium Influx and Mitochondrial Signaling Pathway.Knockdown of Yin Yang 1 enhances anticancer effects of cisplatin through protein phosphatase 2A-mediated T308 dephosphorylation of AKT.
P2860
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P2860
Rituximab-mediated cell signaling and chemo/immuno-sensitization of drug-resistant B-NHL is independent of its Fc functions.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Rituximab-mediated cell signal ...... dependent of its Fc functions.
@en
Rituximab-mediated cell signal ...... dependent of its Fc functions.
@nl
type
label
Rituximab-mediated cell signal ...... dependent of its Fc functions.
@en
Rituximab-mediated cell signal ...... dependent of its Fc functions.
@nl
prefLabel
Rituximab-mediated cell signal ...... dependent of its Fc functions.
@en
Rituximab-mediated cell signal ...... dependent of its Fc functions.
@nl
P2093
P50
P1476
Rituximab-mediated cell signal ...... ndependent of its Fc functions
@en
P2093
Ali R Jazirehi
Benjamin Bonavida
Bernardo Martinez-Miguel
Kandasamy Hariharan
Melisa Martinez-Paniagua
Nabil Hanna
Paul Chinn
Sara Huerta-Yepez
P304
P356
10.1158/1078-0432.CCR-09-1234
P407
P577
2009-10-27T00:00:00Z