Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

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Synthesis of novel and potent vorapaxar analogues.Octahydrocyclopenta[c]pyridine and octahydrocyclopenta[c]pyran analogues as a protease activated receptor 1 (PAR1) antagonist.

P2860

Q53159606-FAD7CE4D-77E5-46FC-88F8-34FEA6499A5E Q53212869-49B00589-D387-44F1-BDC9-7EAA3929D6E4

P2860

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

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http://www.wikidata.org/entity/Q39785906

description

2014 nî lūn-bûn

@nan

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

@en

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

@nl

type

Item

label

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

@en

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

@nl

prefLabel

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

@en

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

@nl

P1476

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

@en

P2093

George Boykow

http://www.w3.org/2001/XMLSchema#string

Ho-Sam Ahn

http://www.w3.org/2001/XMLSchema#string

Hsingan Tsai

http://www.w3.org/2001/XMLSchema#string

Keith Eagen

http://www.w3.org/2001/XMLSchema#string

Madhu Chintala

http://www.w3.org/2001/XMLSchema#string

Mariappan V Chelliah

http://www.w3.org/2001/XMLSchema#string

Samuel Chackalamannil

http://www.w3.org/2001/XMLSchema#string

Stan Kurowski

http://www.w3.org/2001/XMLSchema#string

William J Greenlee

http://www.w3.org/2001/XMLSchema#string

Yan Xia

http://www.w3.org/2001/XMLSchema#string

P2860

The discovery of aspirin's antithrombotic effects

High-resolution crystal structure of human protease-activated receptor 1

Thrombin-receptor antagonist vorapaxar in acute coronary syndromes.

Vorapaxar in the secondary prevention of atherothrombotic events.

Current concepts on antiplatelet therapy: focus on the novel thienopyridine and non-thienopyridine agents.

Discovery of a novel, orally active himbacine-based thrombin receptor antagonist (SCH 530348) with potent antiplatelet activity.

Protease-activated receptors in the cardiovascular system.

Protease-activated receptors in hemostasis, thrombosis and vascular biology.

Thrombin receptor (protease activated receptor-1) antagonists as potent antithrombotic agents with strong antiplatelet effects.

Platelet activation and atherothrombosis.

P304

561-565

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P31

scholarly article

P356

10.1021/ML500008W

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P433

http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

P577

2014-03-11T00:00:00Z

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24900880

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P932

4027741

http://www.w3.org/2001/XMLSchema#string

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

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P2860

P2860

Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

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type

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prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932