Defective gene expression, S phase progression, and maturation during hematopoiesis in E2F1/E2F2 mutant mice.
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Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiationImpaired DNA replication within progenitor cell pools promotes leukemogenesis.Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor ImmunityThe E2F2 transcription factor sustains hepatic glycerophospholipid homeostasis in miceA role for E2F activities in determining the fate of Myc-induced lymphomagenesisRepression by RB1 characterizes genes involved in the penultimate stage of erythroid developmentA highly conserved regulatory element controls hematopoietic expression of GATA-2 in zebrafishDirect binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesisEarly aberrant DNA methylation events in a mouse model of acute myeloid leukemia.Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice.A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor.RNAi-mediated knockdown of E2F2 inhibits tumorigenicity of human glioblastoma cells.Differential proteomics analysis reveals a role for E2F2 in the regulation of the Ahr pathway in T lymphocytes.E2f1-3 are critical for myeloid development.Impact of natural genetic variation on gene expression dynamics.Critical roles for macrophages in islet angiogenesis and maintenance during pancreatic degenerationMouse development with a single E2F activator.Ineffective erythropoiesis with reduced red blood cell survival in serotonin-deficient miceGenome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells.Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesisDeregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts.The development of diabetes in E2f1/E2f2 mutant mice reveals important roles for bone marrow-derived cells in preventing islet cell loss.Dp1 is largely dispensable for embryonic development.p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes.Codanin-1, the protein encoded by the gene mutated in congenital dyserythropoietic anemia type I (CDAN1), is cell cycle-regulated.EKLF/KLF1 controls cell cycle entry via direct regulation of E2f2.Nitric oxide inactivates the retinoblastoma pathway in chronic inflammation.Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism.Congenital dyserythropoietic anemias: molecular insights and diagnostic approachFailure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2.A role for transcription factor E2F2 in hepatocyte proliferation and timely liver regeneration.Functional interrelationship between TFII-I and E2F transcription factors at specific cell cycle gene loci.Zfp521 promotes B-cell viability and cyclin D1 gene expression in a B cell culture system.E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated ErythroblastsGlobal analysis of induced transcription factors and cofactors identifies Tfdp2 as an essential coregulator during terminal erythropoiesis.The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts.EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation.TRIB2 regulates normal and stress-induced thymocyte proliferation.The transcriptional profiling of human in vivo-generated plasma cells identifies selective imbalances in monoclonal gammopathies
P2860
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P2860
Defective gene expression, S phase progression, and maturation during hematopoiesis in E2F1/E2F2 mutant mice.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Defective gene expression, S p ...... esis in E2F1/E2F2 mutant mice.
@en
Defective gene expression, S p ...... esis in E2F1/E2F2 mutant mice.
@nl
type
label
Defective gene expression, S p ...... esis in E2F1/E2F2 mutant mice.
@en
Defective gene expression, S p ...... esis in E2F1/E2F2 mutant mice.
@nl
prefLabel
Defective gene expression, S p ...... esis in E2F1/E2F2 mutant mice.
@en
Defective gene expression, S p ...... esis in E2F1/E2F2 mutant mice.
@nl
P2093
P2860
P1476
Defective gene expression, S p ...... iesis in E2F1/E2F2 mutant mice
@en
P2093
Christopher J Hogan
Jing W Zhu
P2860
P304
P356
10.1128/MCB.23.10.3607-3622.2003
P407
P50
P577
2003-05-01T00:00:00Z