Drosophila SETs its sights on cancer: Trr/MLL3/4 COMPASS-like complexes in development and disease. - Wikidata - awgldk - TriplyDB

Drosophila SETs its sights on cancer: Trr/MLL3/4 COMPASS-like complexes in development and disease.

Drosophila SETs its sights on cancer: Trr/MLL3/4 COMPASS-like complexes in development and disease.

http://www.wikidata.org/entity/Q39788356

about

Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.Setd1a regulates progenitor B-cell-to-precursor B-cell development through histone H3 lysine 4 trimethylation and Ig heavy-chain rearrangement.An Lnc RNA (GAS5)/SnoRNA-derived piRNA induces activation of TRAIL gene by site-specifically recruiting MLL/COMPASS-like complexes.WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission.Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse.Enhancer biology and enhanceropathies.Downregulation of MLL3 in esophageal squamous cell carcinoma is required for the growth and metastasis of cancer cells.hSETD1A regulates Wnt target genes and controls tumor growth of colorectal cancer cells.Evolving Catalytic Properties of the MLL Family SET Domain.Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy

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P2860

Drosophila SETs its sights on cancer: Trr/MLL3/4 COMPASS-like complexes in development and disease.

http://www.wikidata.org/entity/Q39788356

description

2013 nî lūn-bûn

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Drosophila SETs its sights on ...... es in development and disease.

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Drosophila SETs its sights on ...... es in development and disease.

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Drosophila SETs its sights on ...... es in development and disease.

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Molecular and Cellular Biology

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Drosophila SETs its sights on ...... es in development and disease.

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Ali Shilatifard

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Marc Alard Morgan

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P2860

Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS

Dissecting the genomic complexity underlying medulloblastoma

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

Mediator and cohesin connect gene expression and chromatin architecture

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

Combinatorial patterns of histone acetylations and methylations in the human genome

The super elongation complex (SEC) and MLL in development and disease.

The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation.

Histone modifications at human enhancers reflect global cell-type-specific gene expression

The genetic landscape of the childhood cancer medulloblastoma

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1698-1701

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scholarly article

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10.1128/MCB.00203-13

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9

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33

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