Centrosomes split in the presence of impaired DNA integrity during mitosis - Wikidata - awgldk - TriplyDB

Centrosomes split in the presence of impaired DNA integrity during mitosis

Centrosomes split in the presence of impaired DNA integrity during mitosis

http://www.wikidata.org/entity/Q39788663

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Single-walled carbon nanotube-induced mitotic disruption Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance The Golgi protein GM130 regulates centrosome morphology and function The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity A novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrity TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering.Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: a novel chemotherapeutic approach.Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells.Oscillation of APC/C activity during cell cycle arrest promotes centrosome amplification.Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion.Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.Chrysotile effects on human lung cell carcinoma in culture: 3-D reconstruction and DNA quantification by image analysis.Mitochondrial genome regulates mitotic fidelity by maintaining centrosomal homeostasis.Centrosomes as signalling centres.The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries.A centrosome-autonomous signal that involves centriole disengagement permits centrosome duplication in G2 phase after DNA damage.Mechanism limiting centrosome duplication to once per cell cycle.AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers.Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable DNA damage induces Chk1-dependent centrosome amplification.Kizuna is a novel mitotic substrate for CDC25B phosphatase New insights into subcomplex assembly and modifications of centrosomal proteins.C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis.Centrosomes are multifunctional regulators of genome stability The centrosome and cell proliferation.14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression.A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instability 53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis Regulation of centrosomes by the BRCA1-dependent ubiquitin ligase A novel role for the deubiquitinase USP1 in the control of centrosome duplication.Mechanisms of metal-induced centrosome amplification.Such small hands: the roles of centrins/caltractins in the centriole and in genome maintenance.Mitotic spindle multipolarity without centrosome amplification.HTLV-1 Tax: centrosome amplification and cancer.Well-plate mechanical confinement platform for studies of mechanical mutagenesis.Centrosome aberrations associated with cellular senescence and p53 localization at supernumerary centrosomes.

P2860

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P2860

Centrosomes split in the presence of impaired DNA integrity during mitosis

http://www.wikidata.org/entity/Q39788663

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

@zh-cn

name

Centrosomes split in the presence of impaired DNA integrity during mitosis

@en

Centrosomes split in the presence of impaired DNA integrity during mitosis.

@nl

type

label

Centrosomes split in the presence of impaired DNA integrity during mitosis

@en

Centrosomes split in the presence of impaired DNA integrity during mitosis.

@nl

prefLabel

Centrosomes split in the presence of impaired DNA integrity during mitosis

@en

Centrosomes split in the presence of impaired DNA integrity during mitosis.

@nl

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MBC.E02-08-0510

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Molecular Biology of the Cell

P1476

Centrosomes split in the presence of impaired DNA integrity during mitosis

@en

P2093

Engbert H Blaauw

http://www.w3.org/2001/XMLSchema#string

Gert W A Van Cappellen

http://www.w3.org/2001/XMLSchema#string

Harm H Kampinga

http://www.w3.org/2001/XMLSchema#string

Henderika M J Hut

http://www.w3.org/2001/XMLSchema#string

Ody C M Sibon

http://www.w3.org/2001/XMLSchema#string

Willy Lemstra

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P2860

NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1

Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome

A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

Centrosome amplification drives chromosomal instability in breast tumor development.

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

Cyclin-dependent kinase control of centrosome duplication

Checkpoints: controls that ensure the order of cell cycle events

Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

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1993-2004

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10.1091/MBC.E02-08-0510

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5

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14

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12802070

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165092

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