Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling. - Wikidata - awgldk - TriplyDB

Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling.

Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling.

http://www.wikidata.org/entity/Q39791119

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The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis Casein kinase 1 α phosphorylates the Wnt regulator Jade-1 and modulates its activity Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor Molecular Mechanisms Regulating Temperature Compensation of the Circadian Clock.Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1 Type 1 interferons contribute to the clearance of senescent cell.Ubiquitination-dependent regulation of signaling receptors in cancer.Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2 Identification of a secreted casein kinase 1 in Leishmania donovani: effect of protein over expression on parasite growth and virulence.Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptor The cell biology of the unfolded protein response.CKI isoforms α and ε regulate Star-PAP target messages by controlling Star-PAP poly(A) polymerase activity and phosphoinositide stimulation.Bcr-abl signals to desensitize chronic myeloid leukemia cells to IFNα via accelerating the degradation of its receptor Activation of the Ras/Raf/MEK pathway facilitates hepatitis C virus replication via attenuation of the interferon-JAK-STAT pathway.From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.Phosphorylation regulates the Star-PAP-PIPKIα interaction and directs specificity toward mRNA targets.Type I interferons mediate pancreatic toxicities of PERK inhibition.The enemy within: Targeting host-parasite interaction for antileishmanial drug discovery Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON Eliminative signaling by Janus kinases: role in the downregulation of associated receptors.Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury.Hope and fear for interferon: the receptor-centric outlook on the future of interferon therapy.Inflammatory signaling compromises cell responses to interferon alpha.Anti-metastatic functions of type 1 interferons: Foundation for the adjuvant therapy of cancer.Type I and III Interferon in the Gut: Tight Balance between Host Protection and Immunopathology.Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses.Matrix Metalloproteinase 9 Facilitates Hepatitis B Virus Replication through Binding with Type I Interferon (IFN) Receptor 1 To Repress IFN/JAK/STAT Signaling.Casein kinase 1α mediates degradation of receptors for type I and type II interferons caused by hemagglutinin of influenza A virus.Type I Interferon Signaling Is Required for CpG-Oligodesoxynucleotide-Induced Control of Leishmania major, but Not for Spontaneous Cure of Subcutaneous Primary or Secondary L. major Infection.Downregulation of the IFNAR1 chain of type 1 interferon receptor contributes to the maintenance of the haematopoietic stem cells.Casein kinase 1α: biological mechanisms and theranostic potential.

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P2860

Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling.

http://www.wikidata.org/entity/Q39791119

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

Mammalian casein kinase 1alpha ...... d type I interferon signaling.

@en

Mammalian casein kinase 1alpha ...... d type I interferon signaling.

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type

label

Mammalian casein kinase 1alpha ...... d type I interferon signaling.

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Mammalian casein kinase 1alpha ...... d type I interferon signaling.

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prefLabel

Mammalian casein kinase 1alpha ...... d type I interferon signaling.

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Mammalian casein kinase 1alpha ...... d type I interferon signaling.

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Molecular and Cellular Biology

P1476

Mammalian casein kinase 1alpha ...... nd type I interferon signaling

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P2093

Christopher J Carbone

http://www.w3.org/2001/XMLSchema#string

Darren P Baker

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K G Suresh Kumar

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K John McLaughlin

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Lucas P Carvalho

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N Adrian Leu

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Peter M Yau

http://www.w3.org/2001/XMLSchema#string

Phillip Scott

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Robert G K Donald

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Sabyasachi Bhattacharya

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P2860

Functional role of type I and type II interferons in antiviral defense

SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor

SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein

Members of a novel family of mammalian protein kinases complement the DNA-negative phenotype of a vaccinia virus ts mutant defective in the B1 kinase

The selectivity of protein kinase inhibitors: a further update

The Isoform of Protein Kinase CKI Is Responsible for Hepatitis C Virus NS5A Hyperphosphorylation

The flaviviral methyltransferase is a substrate of Casein Kinase 1

How cells respond to interferons

A road map for those who don't know JAK-STAT

The casein kinase 1 family: participation in multiple cellular processes in eukaryotes

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6401-6412

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scholarly article

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10.1128/MCB.00478-09

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P433

24

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P478

29

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Mitchell J Weiss

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2009-10-05T00:00:00Z

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19805514

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2786868

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