Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells. - Wikidata - awgldk - TriplyDB

Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells.

Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells.

http://www.wikidata.org/entity/Q39794629

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Redox Regulation in Cancer Stem Cells STAT3: A Novel Molecular Mediator of Resistance to Chemoradiotherapy Current and future targeted therapies for non-small-cell lung cancers with aberrant EGF receptors Cucurbitacin I Attenuates Cardiomyocyte Hypertrophy via Inhibition of Connective Tissue Growth Factor (CCN2) and TGF- β/Smads Signalings Clinicopathological significance of cancer stem cells marked by CD133 and KAI1/CD82 expression in laryngeal squamous cell carcinoma.Low nanomolar concentrations of Cucurbitacin-I induces G2/M phase arrest and apoptosis by perturbing redox homeostasis in gastric cancer cells in vitro and in vivo Therapeutic modulators of STAT signalling for human diseases Emerging role of nanog in tumorigenesis and cancer stem cells.Cucurbitacin I blocks cerebrospinal fluid and platelet derived growth factor-BB stimulation of leptomeningeal and meningioma DNA synthesis.Ethanol extract of Forsythia suspensa root induces apoptosis of esophageal carcinoma cells via the mitochondrial apoptotic pathway.G protein-coupled receptor 87 (GPR87) promotes the growth and metastasis of CD133⁺ cancer stem-like cells in hepatocellular carcinoma Role of STAT3 in lung cancer.Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer.Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells Targeting Stat3 abrogates EGFR inhibitor resistance in cancer.Resistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrest Cancer stem cells and chemoresistance: The smartest survives the raid Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer.Combined radio- and chemotherapy for non-small cell lung cancer: systematic review of landmark studies based on acquired citations.Cell-based phenotypic screening of mast cell degranulation unveils kinetic perturbations of agents targeting phosphorylation.Cancer stem cells, microRNAs, and therapeutic strategies including natural products.Implication of cancer stem cells in cancer drug development and drug delivery.CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges.Terpenoids: natural products for cancer therapy.Expression of cancer stem cell marker during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity.Knockdown of the T-box transcription factor Brachyury increases sensitivity of adenoid cystic carcinoma cells to chemotherapy and radiation in vitro: implications for a new therapeutic principle.Effect of cytokine-induced killer cells on immune function in patients with lung cancer.Activation of D2 Dopamine Receptors in CD133+ve Cancer Stem Cells in Non-small Cell Lung Carcinoma Inhibits Proliferation, Clonogenic Ability, and Invasiveness of These Cells.Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target.JSI124 inhibits breast cancer cell growth by suppressing the function of B cells via the downregulation of signal transducer and activator of transcription 3.Expression patterns of cancer stem cell markers ALDH1 and CD133 correlate with a high risk of malignant transformation of oral leukoplakia.Eukaryotic Initiation Factor 5A2 Contributes to the Maintenance of CD133(+) Hepatocellular Carcinoma Cells via the c-Myc/microRNA-29b Axis.Collagen XVII/laminin-5 activates epithelial-to-mesenchymal transition and is associated with poor prognosis in lung cancer.Cucurbitacin I Protects H9c2 Cardiomyoblasts against H2O2-Induced Oxidative Stress via Protection of Mitochondrial Dysfunction.[Screening and identification of novel drug-resistant genes in CD133+ and CD133- lung adenosarcoma cells using cDNA microarray].

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Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells.

http://www.wikidata.org/entity/Q39794629

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Cucurbitacin I inhibits tumori ...... -derived CD133-positive cells.

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Cucurbitacin I inhibits tumori ...... -derived CD133-positive cells.

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Cucurbitacin I inhibits tumori ...... -derived CD133-positive cells.

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Cucurbitacin I inhibits tumori ...... -derived CD133-positive cells.

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Ching Tzao

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Han-Shui Hsu

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Hsin-Chin Shih

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Ling-Ming Tseng

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Shih-Chieh Hung

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Shih-Hwa Chiou

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Yi-Wei Chen

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Yu-Chih Chen

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Yuh-Lih Chang

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P2860

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

Identification and expansion of human colon-cancer-initiating cells

Identification of human brain tumour initiating cells

Identification and expansion of the tumorigenic lung cancer stem cell population

CD133: molecule of the moment

Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in nonsmoking lung cancer

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

The STATs of cancer--new molecular targets come of age

Stat3 as an oncogene

STATs in oncogenesis

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10.1002/CNCR.25869

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