PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
about
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersTargeting the Pim kinases in multiple myelomaTargeting Pim kinases for cancer treatment: opportunities and challengesThe PIM kinases in hematological cancersPIM1 kinase as a target for cancer therapyFragment-hopping-based discovery of a novel chemical series of proto-oncogene PIM-1 kinase inhibitorsConditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasiaPim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity.Pim-1 kinase protects mitochondrial integrity in cardiomyocytes.Pathophysiological roles of Pim-3 kinase in pancreatic cancer development and progression.Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1.A review of the mammalian unfolded protein response.Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells.Transcriptional Response to Acute Thermal Exposure in Juvenile Chinook Salmon Determined by RNAseq.PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cellsAntitumor indolequinones induced apoptosis in human pancreatic cancer cells via inhibition of thioredoxin reductase and activation of redox signaling.A Novel Cinnamon-Related Natural Product with Pim-1 Inhibitory Activity Inhibits Leukemia and Skin CancerCell cycle-dependent Cdc25C phosphatase determines cell survival by regulating apoptosis signal-regulating kinase 1Pim Kinase Interacts with Nonstructural 5A Protein and Regulates Hepatitis C Virus Entry.PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma.Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice.Cross-talk between Arg methylation and Ser phosphorylation modulates apoptosis signal-regulating kinase 1 activation in endothelial cells.PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value.Why target PIM1 for cancer diagnosis and treatment?The PIM family of serine/threonine kinases in cancer.PIM kinases: an overview in tumors and recent advances in pancreatic cancer.Pim kinases in hematological malignancies: where are we now and where are we going?PIM kinase (and Akt) biology and signaling in tumors.Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas.Pim kinase isoforms: devils defending cancer cells from therapeutic and immune attacks.p90 RSK2 mediates antianoikis signals by both transcription-dependent and -independent mechanisms.Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress.Dynamic Phosphorylation of Apoptosis Signal Regulating Kinase 1 (ASK1) in Response to Oxidative and Electrophilic Stress.Decreased levels of circulating and tissue miR-107 in human esophageal cancer.Pim1 supports human colorectal cancer growth during glucose deprivation by enhancing the Warburg effect.
P2860
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P2860
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
@en
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
@nl
type
label
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
@en
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
@nl
prefLabel
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
@en
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
@nl
P2093
P2860
P356
P1433
P1476
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2009.276
P407
P577
2009-09-14T00:00:00Z