Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation.
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Autophagy modulation as a target for anticancer drug discoveryAntileishmanial activity of the estrogen receptor modulator raloxifeneIdentification of small molecules enhancing autophagic function from drug network analysis.Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands.Discovery of drug mode of action and drug repositioning from transcriptional responses.Apoptosis and autophagy in breast cancer cells following exemestane treatment.The contribution of lysosomotropism to autophagy perturbation.Targeted excision of VCP R155H mutation by Cre-LoxP technology as a promising therapeutic strategy for valosin-containing protein disease.Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR/S6K Pathway in Breast Cancer Cells.Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophilesHypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells.Insulin-like growth factor 1 attenuates antiestrogen- and antiprogestin-induced apoptosis in ER+ breast cancer cells by MEK1 regulation of the BH3-only pro-apoptotic protein BimLysosomal adaptation: How cells respond to lysosomotropic compounds.Molecular and Biochemical Analysis of the Estrogenic and Proliferative Properties of Vitamin E Compounds.Autophagy inhibition enhances apigenin-induced apoptosis in human breast cancer cellsCritical roles for nitric oxide and ERK in the completion of prosurvival autophagy in 4OHTAM-treated estrogen receptor-positive breast cancer cells.Tamoxifen synergizes with 4-(E)-{(4-hydroxyphenylimino)-methylbenzene, 1,2-diol} and 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, novel azaresveratrol analogs, in inhibiting the proliferation of breast cancer cells.Vitamin C suppresses cell death in MCF-7 human breast cancer cells induced by tamoxifen.Sex hormones and lipoprotein(a) concentration.Modulating autophagy: a strategy for cancer therapyPharmacological modulation of autophagy during cardiac stress.Autophagy: a potential therapeutic target in lung diseases.Activation of autophagy of aggregation-prone ubiquitinated proteins by timosaponin A-IIIUp-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity.Mechanisms of autophagy and apoptosis: Recent developments in breast cancer cells.Autophagic regulation of cell growth by altered expression of Beclin 1 in triple-negative breast cancer.Discovery of 2'-hydroxychalcones as autophagy inducer in A549 lung cancer cells.S6K1 inhibition enhances tamoxifen-induced cell death in MCF-7 cells through translational inhibition of Mcl-1 and survivin.The Role of Oxysterols in Human Cancer.Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis.Dendrogenin A drives LXR to trigger lethal autophagy in cancers.A highly fluorescent AIE-active theranostic agent with anti-tumor activity to specific cancer cells.
P2860
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P2860
Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Tamoxifen and AEBS ligands ind ...... lation of sterol accumulation.
@en
Tamoxifen and AEBS ligands ind ...... lation of sterol accumulation.
@nl
type
label
Tamoxifen and AEBS ligands ind ...... lation of sterol accumulation.
@en
Tamoxifen and AEBS ligands ind ...... lation of sterol accumulation.
@nl
prefLabel
Tamoxifen and AEBS ligands ind ...... lation of sterol accumulation.
@en
Tamoxifen and AEBS ligands ind ...... lation of sterol accumulation.
@nl
P356
P1433
P1476
Tamoxifen and AEBS ligands ind ...... ulation of sterol accumulation
@en
P2093
Marc Poirot
Philippe de Medina
P304
P356
10.4161/AUTO.5.7.9820
P577
2009-10-13T00:00:00Z