Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation.
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The de novo DNA methyltransferase DNMT3A in development and cancerChromatin structure of pluripotent stem cells and induced pluripotent stem cells.DNMT3A and TET2 in the Pre-Leukemic Phase of Hematopoietic DisordersPotential epigenetic mechanism(s) associated with the persistence of psychoneurological symptoms in women receiving chemotherapy for breast cancer: a hypothesisThe recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.Deep sequencing reveals increased DNA methylation in chronic rat epilepsy.Runx1 regulation of Pu.1 corepressor/coactivator exchange identifies specific molecular targets for leukemia differentiation therapy.Integrated epigenome profiling of repressive histone modifications, DNA methylation and gene expression in normal and malignant urothelial cells.DNMT3A in haematological malignancies.Genomic insights into cancer-associated aberrant CpG island hypermethylationGenome-wide methylation and expression differences in HPV(+) and HPV(-) squamous cell carcinoma cell lines are consistent with divergent mechanisms of carcinogenesis.Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesisRegulation and function of DNA methylation in plants and animals.Epigenetics of Epileptogenesis-Evoked Upregulation of Matrix Metalloproteinase-9 in HippocampusOverexpression of the Heterochromatinization Factor BAHD1 in HEK293 Cells Differentially Reshapes the DNA Methylome on Autosomes and X Chromosome.Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes.Multifaceted role of EZH2 in breast and prostate tumorigenesis: epigenetics and beyond.E2f6-mediated repression of the meiotic Stag3 and Smc1β genes during early embryonic development requires Ezh2 and not the de novo methyltransferase Dnmt3b.STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer.Epigenetics of oropharyngeal squamous cell carcinoma: opportunities for novel chemotherapeutic targets.Gene silencing by the Polycomb group proteins and associations with cancer.DNA methylation, ageing and the influence of early life nutrition.Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability.Domain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.Redistribution of H3K27me3 and acetylated histone H4 upon exposure to azacitidine and decitabine results in de-repression of the AML1/ETO target gene IL3.Targeting DNA hypermethylation: computational modeling of DNA demethylation treatment of acute myeloid leukemia.The Regulatory Capacity of Bivalent Genes-A Theoretical Approach.A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets.Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes.dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.Association of large noncoding RNA HOTAIR expression and its downstream intergenic CpG island methylation with survival in breast cancer.Emerging therapeutic targets in myeloproliferative neoplasms and peripheral T-cell leukemia and lymphomas.Linking DNA Damage and Age-Related Promoter DNA Hyper-Methylation in the Intestine.Tamoxifen resistance in breast cancer is regulated by the EZH2-ERα-GREB1 transcriptional axis.Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma.The Polycomb group protein MEDEA and the DNA methyltransferase MET1 interact to repress autonomous endosperm development in Arabidopsis.Epigenetic alterations to Polycomb targets precede malignant transition in a mouse model of breast cancer.
P2860
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P2860
Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Targeting of EZH2 to a defined ...... t not de novo DNA methylation.
@en
Targeting of EZH2 to a defined ...... t not de novo DNA methylation.
@nl
type
label
Targeting of EZH2 to a defined ...... t not de novo DNA methylation.
@en
Targeting of EZH2 to a defined ...... t not de novo DNA methylation.
@nl
prefLabel
Targeting of EZH2 to a defined ...... t not de novo DNA methylation.
@en
Targeting of EZH2 to a defined ...... t not de novo DNA methylation.
@nl
P2093
P356
P1433
P1476
Targeting of EZH2 to a defined ...... ut not de novo DNA methylation
@en
P2093
Lucia L Lam
Margaret Rush
Preeti Goyal
Ruth Appanah
Sandra Lee
P304
P356
10.4161/EPI.4.6.9392
P577
2009-08-29T00:00:00Z