GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib. - Wikidata - awgldk - TriplyDB

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

http://www.wikidata.org/entity/Q39807121

about

Melanoma and the Unfolded Protein Response Endoplasmic reticulum chaperones and oxidoreductases: critical regulators of tumor cell survival and immunorecognition Advances in the understanding of mechanisms and therapeutic use of bortezomib The unfolded protein response in retinal vascular diseases: implications and therapeutic potential beyond protein folding Development of Novel Immunotherapies for Multiple Myeloma Trial Watch: Proteasomal inhibitors for anticancer therapy Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways HKH40A downregulates GRP78/BiP expression in cancer cells.The Par-4-GRP78 TRAIL, more twists and turns.GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the β-catenin signaling.Endoplasmic reticulum stress and cancer.Glucose regulated protein 78 promotes cell invasion via regulation of uPA production and secretion in colon cancer cells.The regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 processing and tumor angiogenesis The critical role of GRP78 in physiologic and pathologic stress.Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system.A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.Endoplasmic reticulum stress in endometrial cancer.GRP78-directed immunotherapy in relapsed or refractory multiple myeloma - results from a phase 1 trial with the monoclonal immunoglobulin M antibody PAT-SM6.Extracellular heat shock proteins: a new location, a new function.Establishment of a human multiple myeloma xenograft model in the chicken to study tumor growth, invasion and angiogenesis.The Aplidin analogs PM01215 and PM02781 inhibit angiogenesis in vitro and in vivo.Sensitizing human multiple myeloma cells to the proteasome inhibitor bortezomib by novel curcumin analogs.Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It.Serum GRP78 as a Tumor Marker and Its Prognostic Significance in Non-Small Cell Lung Cancers: A Retrospective Study.Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting Cripto/GRP78 modulation of the TGF-β pathway in development and oncogenesis Acetylation modification regulates GRP78 secretion in colon cancer cells.The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers.Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: a form of communication during injury, infection, and cell damage. It is never known how far a controversial finding will go! Dedicated to Ferruccio Rito Type I cryoglobulinemia in multiple myeloma, a rare entity: analysis of clinical and biological characteristics of seven cases and review of the literature.Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential The double-edged sword: conserved functions of extracellular hsp90 in wound healing and cancer.Elucidation of a novel phenformin derivative on glucose-deprived stress responses in HT-29 cells.A novel combination treatment for breast cancer cells involving BAPTA-AM and proteasome inhibitor bortezomib.GRP78 mediates cell growth and invasiveness in endometrial cancer.The proteasome inhibitor bortezomib is a potent inducer of zinc finger AN1-type domain 2a gene expression: role of heat shock factor 1 (HSF1)-heat shock factor 2 (HSF2) heterocomplexes.Unconventional Secretion of Heat Shock Proteins in Cancer.The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling

P2860

Q26765426-86E903AE-1146-4D08-BD51-C095DCF03B42 Q26823628-DCF04147-CAE0-458F-94C6-EA65928EB025 Q26849940-684C0A34-139A-4E4D-A5F0-98269E0BA51D Q26852080-5039EE44-C3A2-447F-952D-D21413C207B4 Q28066890-48002FEB-257B-4B93-8EB1-8DA3F1D85B63 Q28082910-62D84D98-1416-423F-B416-02AA6E6565C4 Q28286344-A3A11340-E890-471D-8CB8-4677EDB75708 Q33720273-463DD198-B777-4E3E-9997-33629F2108F3 Q33768428-5CFA9E3B-5778-45FA-A3E3-A3B6AB2216E4 Q34221624-BB7A49C6-6211-455D-90D4-AEDD471F9897 Q34376123-3D75CD4E-F863-4267-B3B6-25E67A6DF12A Q34389707-76DC88B1-A097-4FFF-B6FD-FDF6E472142B Q34401008-6E070392-4DDF-4571-9A6D-887FBA8A7473 Q34594217-F104541F-81E0-43A7-AAB2-EEA73A56B294 Q34788381-58531BD2-026A-47A8-B7E9-88EFA12A1552 Q34803685-B759D8FA-750A-4006-9CA7-69FEE82528C0 Q34923990-87D709F1-F585-4B4A-90AF-6B693E4E5525 Q34928094-62635189-CD62-44F5-B3CB-B90EA2A64850 Q35146307-E0FF5D15-B1BE-46F5-952E-6D75AD238E69 Q35153907-417DD39D-E28E-43CC-ACF5-81D5AAA73D2D Q35636675-328A98ED-DBB1-4F2E-856F-7E5FBCF5D29C Q35813841-690160DB-F504-4003-86BD-D54D101DDE81 Q35840019-A386DD39-22CF-4B2F-9FCF-3D5188716143 Q35899925-4821BEED-4043-4A88-9B45-0F4CEDE0A8A9 Q35912759-05840E5E-7246-4B99-A688-6FA3F5B0B249 Q35964550-67D0DED9-9E7E-44C4-AFD3-D50238FAEF51 Q37045189-4EE249BD-01F5-43C5-A225-4049E2AFD078 Q37128282-B6AB722E-E482-4D86-83D4-ABA8C17AFDD9 Q37285838-BBFCFDAF-2131-49B8-8C3C-7436DD3A3627 Q37449406-09A4B473-3FE9-4473-A02D-54643C9B7B1A Q37801877-6903A5BF-462D-48C0-B9B6-73F3E584340F Q37990030-ABD26EF4-D026-45F8-A17C-579731F7D9BD Q38198491-1F071CD1-A8D5-4DF3-B61E-49314EC1E5DC Q38210012-DFA4895D-98A3-44FD-92DB-5F59148AE432 Q38759120-520209D2-0371-405F-9012-DA17B4445390 Q38761740-2A0DAF43-E96E-4B91-9854-B00E04909281 Q39024022-28C7511E-92C3-44EE-9A11-F8ED22F036CF Q39146191-36AB744A-34FB-42B5-8854-82A7966A7C29 Q39281019-1D3EE144-129D-4443-BB73-AA5318FA27C1 Q39304490-D45D8475-9AED-4392-9F80-BD146CE2C07F

P2860

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

http://www.wikidata.org/entity/Q39807121

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

@en

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

@nl

type

label

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

@en

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

@nl

prefLabel

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

@en

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

@nl

P1433

Q39807121-25BAB189-A9E9-42C6-A56D-51E10F9390B9

P1476

Q39807121-53482937-661B-434B-BA14-2FDC698F343A

P2093

Q39807121-9D6F0B03-C463-4119-8CF0-815BA26B8B4B

Q39807121-A69B1D2A-7316-4168-9817-BC8D2CE37004

Q39807121-BBA9DA5E-A16A-45B0-9025-3C4BA8320527

Q39807121-C01F8BA5-FBE4-4834-B5BC-1055F25A3333

Q39807121-D6F6BE88-2F0E-46BA-8F01-6E0386738C98

Q39807121-EC797704-1D46-47D8-A819-F3E3565CE489

Q39807121-FBD497F4-235B-43B9-87F5-310A89D23879

P304

Q39807121-1811485C-11C9-4E97-B53C-A6CA4CAB1145

P31

Q39807121-41795587-0F4F-4397-AB74-392549AC3A9A

P356

Q39807121-8319A9B0-9441-4C68-A1AC-6E4A1F5629DA

P407

Q39807121-FE14220D-989D-43BC-9D15-1E1E22E86015

P433

Q39807121-30DF58E2-AA3B-46CF-8C81-8365DB7443DB

P478

Q39807121-608CB27B-9016-4054-8982-0C8E81B1093E

P577

Q39807121-2E3FC5F3-C630-40A9-BA23-CFA220CCCAE9

P5875

Q39807121-9A4562FE-1800-44D2-BE8C-FF7363D8DBD5

P698

Q39807121-F658A87B-19E2-4D72-A610-BB099798A5C2

P356

BLOOD-2009-03-209668

P1433

P1476

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib.

@en

P2093

Bettina Sarg

http://www.w3.org/2001/XMLSchema#string

Christoph Zenzmaier

http://www.w3.org/2001/XMLSchema#string

Eberhard Gunsilius

http://www.w3.org/2001/XMLSchema#string

Gerold Untergasser

http://www.w3.org/2001/XMLSchema#string

Guenther Gastl

http://www.w3.org/2001/XMLSchema#string

Johann Kern

http://www.w3.org/2001/XMLSchema#string

Michael Steurer

http://www.w3.org/2001/XMLSchema#string

P304

3960-3967

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1182/BLOOD-2009-03-209668

http://www.w3.org/2001/XMLSchema#string

P407

P433

18

http://www.w3.org/2001/XMLSchema#string

P478

114

http://www.w3.org/2001/XMLSchema#string

P577

2009-08-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26773369

http://www.w3.org/2001/XMLSchema#string

P698

19713465

http://www.w3.org/2001/XMLSchema#string