Architectural and thermodynamic principles underlying intramembrane protease function.
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Large Lateral Movement of Transmembrane Helix S5 Is Not Required for Substrate Access to the Active Site of Rhomboid Intramembrane ProteaseProteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate AffinityA Trichomonas vaginalis Rhomboid Protease and Its Substrate Modulate Parasite Attachment and Cytolysis of Host CellsMembrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.Structure and mechanism of rhomboid proteaseAn internal water-retention site in the rhomboid intramembrane protease GlpG ensures catalytic efficiency.A rhomboid protease gene deletion affects a novel oligosaccharide N-linked to the S-layer glycoprotein of Haloferax volcaniiSubstrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structuresCooperative folding of a polytopic α-helical membrane protein involves a compact N-terminal nucleus and nonnative loops.Roles of the membrane-reentrant β-hairpin-like loop of RseP protease in selective substrate cleavageMembrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics.Topological constraints and modular structure in the folding and functional motions of GlpG, an intramembrane protease.Steric trapping reveals a cooperativity network in the intramembrane protease GlpGMapping the energy landscape for second-stage folding of a single membrane protein.Structural and mechanistic principles of intramembrane proteolysis--lessons from rhomboids.The safety dance: biophysics of membrane protein folding and misfolding in a cellular contextCrystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid ProteolysisWhy cells need intramembrane proteases - a mechanistic perspective.Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport.An Inducible Reconstitution System for the Real-Time Kinetic Analysis of Protease Activity and Inhibition Inside the Membrane.Applications of Single-Molecule Methods to Membrane Protein Folding Studies.Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein.Reversible Unfolding of Rhomboid Intramembrane ProteasesCytosolic extensions directly regulate a rhomboid protease by modulating substrate gating.A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP.How γ-secretase hits a moving target.Documentation of an Imperative To Improve Methods for Predicting Membrane Protein Stability.Structure formation during translocon-unassisted co-translational membrane protein folding.Influence of hydrophobic mismatch on the catalytic activity of Escherichia coli GlpG rhomboid protease.Interrogating Membrane Protein Conformational Dynamics within Native Lipid Compositions.Membrane properties that shape the evolution of membrane enzymes.Folding-Degradation Relationship of a Membrane Protein Mediated by the Universally Conserved ATP-Dependent Protease FtsH.
P2860
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P2860
Architectural and thermodynamic principles underlying intramembrane protease function.
description
2012 nî lūn-bûn
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2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Architectural and thermodynamic principles underlying intramembrane protease function.
@en
Architectural and thermodynamic principles underlying intramembrane protease function.
@nl
type
label
Architectural and thermodynamic principles underlying intramembrane protease function.
@en
Architectural and thermodynamic principles underlying intramembrane protease function.
@nl
prefLabel
Architectural and thermodynamic principles underlying intramembrane protease function.
@en
Architectural and thermodynamic principles underlying intramembrane protease function.
@nl
P2860
P356
P1476
Architectural and thermodynamic principles underlying intramembrane protease function.
@en
P2093
Rosanna P Baker
Sinisa Urban
P2860
P2888
P304
P356
10.1038/NCHEMBIO.1021
P577
2012-07-15T00:00:00Z