Identification of cellular and viral factors related to anti-hepatitis C virus activity of cyclophilin inhibitor.
about
Identification of cyclophilin-40-interacting proteins reveals potential cellular function of cyclophilin-40Chaperones in hepatitis C virus infectionGenetic characterization of hepatitis C virus in long-term RNA replication using Li23 cell culture systemsDEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5ARandomised clinical trial: alisporivir combined with peginterferon and ribavirin in treatment-naïve patients with chronic HCV genotype 1 infection (ESSENTIAL II).A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approachNew antiviral therapies for chronic hepatitis CDomain 3 of NS5A protein from the hepatitis C virus has intrinsic alpha-helical propensity and is a substrate of cyclophilin A.Cyclosporin A inhibits the replication of diverse coronavirusesPhenotypic analysis of NS5A variant from liver transplant patient with increased cyclosporine susceptibilityAnti-HCV drugs in the pipeline.Proteomic identification of cyclophilin A as a potential biomarker and therapeutic target in oral submucous fibrosis.Cyclophilin inhibitors: a novel class of promising host-targeting anti-HCV agents.Cyclophilin involvement in the replication of hepatitis C virus and other viruses.Cyclophilins as modulators of viral replication.The role of immunophilins in viral infection.Cyclophilin inhibitors as a novel HCV therapy.Multiple mutations in hepatitis C virus NS5A domain II are required to confer a significant level of resistance to alisporivirPreclinical characterization of naturally occurring polyketide cyclophilin inhibitors from the sanglifehrin family.Cyclophilin A-independent recruitment of NS5A and NS5B into hepatitis C virus replication complexes.HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors.The cyclophilin inhibitor SCY-635 disrupts hepatitis C virus NS5A-cyclophilin A complexes.
P2860
Q24314639-EC0292BD-AE5A-4130-8940-C5B84BDE83F5Q26771251-3DC3387C-201A-4D71-B569-326BC4E52766Q28540849-8EE38DCD-0DD9-4961-A1F4-4CCE32F8962BQ28748683-50194381-1736-4B8E-95DB-AD2BF3C0E8A6Q33424900-E414EBC8-0F49-408C-A318-18F158B8C839Q33707739-20DAC77E-9FA8-44CE-BFAE-1267A6225033Q34130399-1E9ABD1A-4F56-43B9-9D1D-B610A0E086EDQ35063336-F1E0C562-AF4F-456B-948B-1D979DA9328BQ35960586-DE95AB2A-4BFE-4EDF-B0B9-891BC299742CQ37144087-2A2FC7DB-FCE5-4601-9938-47E9F0AD786AQ37177740-09E7DCF7-B228-4FDC-B939-F6B3E2966DEBQ37645025-C22A1B00-4410-4161-B433-7CBF6642D2D5Q37968485-A981A89A-FDD4-4E22-AD03-50B5BD1B0487Q38040256-AA42AC8C-2AC7-49A5-BD03-0D237A2B55D7Q38121470-C2456907-3548-42EC-8B60-997206D2701EQ38274889-D554281E-521B-4E0A-9506-A3213A33AA93Q38615621-878F745C-7778-4955-AEA6-E5BB77AFD924Q39313413-D5ADB97A-693C-464E-A86E-0EAEFFCF898AQ39579921-0CD7ECC0-19BC-4C16-B916-32B3FBD12DCFQ39747173-D3351CA9-40C1-49C6-91E0-020C444B0D0BQ40998392-0DAFC2AD-0127-4546-B6DA-D2D7D47D11C6Q41843629-7C3C4A82-1DBD-415F-B4E2-7755C2F661AC
P2860
Identification of cellular and viral factors related to anti-hepatitis C virus activity of cyclophilin inhibitor.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Identification of cellular and ...... vity of cyclophilin inhibitor.
@en
Identification of cellular and ...... vity of cyclophilin inhibitor.
@nl
type
label
Identification of cellular and ...... vity of cyclophilin inhibitor.
@en
Identification of cellular and ...... vity of cyclophilin inhibitor.
@nl
prefLabel
Identification of cellular and ...... vity of cyclophilin inhibitor.
@en
Identification of cellular and ...... vity of cyclophilin inhibitor.
@nl
P2093
P1433
P1476
Identification of cellular and ...... vity of cyclophilin inhibitor.
@en
P2093
Daisuke Inoue
Koichi Watashi
Kunitada Shimotohno
Makoto Hijikata
P2860
P304
P356
10.1111/J.1349-7006.2009.01263.X
P577
2009-06-26T00:00:00Z