Kinome profiling in pediatric brain tumors as a new approach for target discovery.
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Dual Inhibitor AEE788 Reduces Tumor Growth in Preclinical Models of MedulloblastomaDifferential inhibition of ex-vivo tumor kinase activity by vemurafenib in BRAF(V600E) and BRAF wild-type metastatic malignant melanomaKinomic profiling of electromagnetic navigational bronchoscopy specimens: a new approach for personalized medicineInhibition of N1-Src kinase by a specific SH3 peptide ligand reveals a role for N1-Src in neurite elongation by L1-CAM.Altered serine/threonine kinase activity in schizophreniaPostmortem brain: an underutilized substrate for studying severe mental illnessVascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells.Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines.New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells.Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action?Dasatinib suppression of medulloblastoma survival and migration is markedly enhanced by combining treatment with the aurora kinase inhibitor AT9283.In comparative analysis of multi-kinase inhibitors for targeted medulloblastoma therapy pazopanib exhibits promising in vitro and in vivo efficacy.Intracellular and extracellular domains of protein tyrosine phosphatase PTPRZ-B differentially regulate glioma cell growth and motilityTumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancerFocal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism.Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymomaHigh Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes.Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell LinesAn in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes.Activity Based High-Throughput Screening for Novel O-GlcNAc Transferase Substrates Using a Dynamic Peptide MicroarrayLinkage between genotype and immunological phenotype in Crohn's diseaseEphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasionMolecular profiling of childhood cancer: Biomarkers and novel therapiesKINOMIC ALTERATIONS IN ATYPICAL MENINGIOMA.Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease PathologyEvaluation of a tyrosine kinase peptide microarray for tyrosine kinase inhibitor therapy selection in cancer.Clinical and kinomic analysis identifies peripheral blood mononuclear cells as a potential pharmacodynamic biomarker in metastatic renal cell carcinoma patients treated with sunitinib.Deciphering enzyme function using peptide arrays.Peptide arrays for kinome analysis: new opportunities and remaining challenges.Kinome profiling.A portable optical waveguide resonance light-scattering scanner for microarray detection.Divergent immune responses to Mycobacterium avium subsp. paratuberculosis infection correlate with kinome responses at the site of intestinal infection.Gene expression profiles and signaling mechanisms in α2B-adrenoceptor-evoked proliferation of vascular smooth muscle cells.Kinase analysis of penile squamous cell carcinoma on multiple platforms to identify potential therapeutic targets.Kinomic profiling identifies focal adhesion kinase 1 as a therapeutic target in advanced clear cell renal cell carcinoma.Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung CancerPreclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma.Can kinomics and proteomics bridge the gap between pediatric cancers and newly designed kinase inhibitors?Approaches for targeting cancer stem cells drug resistance.Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL).
P2860
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P2860
Kinome profiling in pediatric brain tumors as a new approach for target discovery.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Kinome profiling in pediatric brain tumors as a new approach for target discovery.
@en
Kinome profiling in pediatric brain tumors as a new approach for target discovery.
@nl
type
label
Kinome profiling in pediatric brain tumors as a new approach for target discovery.
@en
Kinome profiling in pediatric brain tumors as a new approach for target discovery.
@nl
prefLabel
Kinome profiling in pediatric brain tumors as a new approach for target discovery.
@en
Kinome profiling in pediatric brain tumors as a new approach for target discovery.
@nl
P2093
P1433
P1476
Kinome profiling in pediatric brain tumors as a new approach for target discovery.
@en
P2093
Arend H Sikkema
Arja ter Elst
Eelco W Hoving
Eveline S J M de Bont
Frank J G Scherpen
Piet J Boender
Rik de Wijn
Rob Ruijtenbeek
Sander H Diks
Wilfred F A den Dunnen
P304
P356
10.1158/0008-5472.CAN-08-3660
P407
P577
2009-06-30T00:00:00Z