Ecto-5'-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis.
about
Crosstalk between purinergic receptors and lipid mediators in leishmaniasisNT5E mutations that cause human disease are associated with intracellular mistrafficking of NT5E proteinAdenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.Caffeine, a drug for all seasons.Pigment epithelium-derived factor is an intrinsic antifibrosis factor targeting hepatic stellate cellsAlternative splicing of human NT5E in cirrhosis and hepatocellular carcinoma produces a negative regulator of ecto-5'-nucleotidase (CD73).Adenosine A2A receptors play an active role in mouse bone marrow-derived mesenchymal stem cell development.Variable penetrance of metabolic phenotypes and development of high-fat diet-induced adiposity in NEIL1-deficient mice.Caffeine inhibits the activation of hepatic stellate cells induced by acetaldehyde via adenosine A2A receptor mediated by the cAMP/PKA/SRC/ERK1/2/P38 MAPK signal pathwayAdenosine receptors and fibrosis: a translational review.Antilipogenic and anti-inflammatory activities of Codonopsis lanceolata in mice hepatic tissues after chronic ethanol feedingCoexpression of ecto-5'-nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver.A cell-based screening assay to identify pharmaceutical compounds that enhance the regenerative quality of corneal repair.Reduced Adenosine Uptake and Its Contribution to Signaling that Mediates Profibrotic Activation in Renal Tubular Epithelial Cells: Implication in Diabetic Nephropathy.New Approaches for Studying Alcoholic Liver DiseaseRecovery of the Cell Cycle Inhibition in CCl(4)-Induced Cirrhosis by the Adenosine Derivative IFC-305.Activated hepatic stellate cells upregulate transcription of ecto-5'-nucleotidase/CD73 via specific SP1 and SMAD promoter elementsEctonucleotidases in solid organ and allogeneic hematopoietic cell transplantationPurinergic signaling in scarring.Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions.TLR9 deficiency promotes CD73 expression in T cells and diabetes protection in nonobese diabetic mice.CD73 (ecto-5'-nucleotidase) hepatocyte levels differ across mouse strains and contribute to mallory-denk body formation.Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3.Ecto-5'-nucleotidase (CD73) regulates host inflammatory responses and exacerbates murine salmonellosis.Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5'-nucleotidase, and alkaline phosphatase inhibitors.Purinergic signalling in the liver in health and disease.Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer.Systemic methotrexate for the treatment of psoriasis.Extracellular adenosine generation in the regulation of pro-inflammatory responses and pathogen colonization.CD73-adenosine: a next-generation target in immuno-oncology.Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases.New role of the human equilibrative nucleoside transporter 1 (hENT1) in epithelial-to-mesenchymal transition in renal tubular cells.Ecto-5'-nucleotidase/CD73 knockdown increases cell migration and mRNA level of collagen I in a hepatic stellate cell line.Adenosine: tipping the balance towards hepatic steatosis and fibrosis.Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung FibrosisExtracellular adenosine controls NKT-cell-dependent hepatitis inductionAdenosine signaling contributes to ethanol-induced fatty liver in mice.In Vivo Acute on Chronic Ethanol Effects in Liver: A Mouse Model Exhibiting Exacerbated Injury, Altered Metabolic and Epigenetic Responses.Anti-metabolic syndrome effects of adenosine ingestion in stroke-prone spontaneously hypertensive rats fed a high-fat diet.
P2860
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P2860
Ecto-5'-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Ecto-5'-nucleotidase (CD73) -m ...... ical role in hepatic fibrosis.
@en
Ecto-5'-nucleotidase
@nl
type
label
Ecto-5'-nucleotidase (CD73) -m ...... ical role in hepatic fibrosis.
@en
Ecto-5'-nucleotidase
@nl
prefLabel
Ecto-5'-nucleotidase (CD73) -m ...... ical role in hepatic fibrosis.
@en
Ecto-5'-nucleotidase
@nl
P2093
P356
P1433
P1476
Ecto-5'-nucleotidase (CD73) -m ...... tical role in hepatic fibrosis
@en
P2093
Edwin S L Chan
Herman Yee
Patricia Fernandez
Tuere Wilder
Zhongsheng Peng
P304
P356
10.1096/FJ.07-100685
P407
P577
2008-02-08T00:00:00Z