Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells.
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Notch Signaling in Neuroendocrine TumorsA Role for Notch Signalling in Breast Cancer and Endocrine ResistanceCancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?Therapeutic targets in the ASK1-dependent stress signaling pathwaysFrom fly wings to targeted cancer therapies: a centennial for notch signalingNotch inhibition as a promising new approach to cancer therapy.Decoding breast cancer tissue-stroma interactions using species-specific sequencingNotch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis.Notch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis.Combined inhibition of ErbB1/2 and Notch receptors effectively targets breast ductal carcinoma in situ (DCIS) stem/progenitor cell activity regardless of ErbB2 status.Notch-EGFR/HER2 Bidirectional Crosstalk in Breast CancerRole of Notch and its oncogenic signaling crosstalk in breast cancer.Propolis augments apoptosis induced by butyrate via targeting cell survival pathways.The emerging importance of α-L-fucose in human breast cancer: a review.Notch signaling as a therapeutic target for breast cancer treatment?Induction of cancer cell death by isoflavone: the role of multiple signaling pathways.Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolide Withaferin Ap53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.Role of the DLL4-NOTCH system in PGF2alpha-induced luteolysis in the pregnant ratγ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells.Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivoCorrelation of Notch1, pAKT and nuclear NF-κB expression in triple negative breast cancer.Combination therapy of RY10-4 with the γ-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer.Gamma secretase inhibitors of Notch signalingSyndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathwaysTargeting Notch to target cancer stem cells.Cancer stem cells: problems for therapy?Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways.TGF-beta-dependent and -independent roles of STRAP in cancer.Notch signalling in solid tumours: a little bit of everything but not all the time.The ubiquitin-proteasome system and signal transduction pathways regulating Epithelial Mesenchymal transition of cancer.The Notch pathway: a novel target for myocardial remodelling therapy?Role of delta-like ligand-4 in chemoresistance against docetaxel in MCF-7 cells.Nicastrin mutations in familial acne inversa impact keratinocyte proliferation and differentiation through the Notch and phosphoinositide 3-kinase/AKT signalling pathways.Involvement of Notch-1 in Resistance to Regorafenib in Colon Cancer Cells.Differential behaviors of trastuzumab-sensitive and -resistant SKBR3 cells treated with menadione reveal the involvement of Notch1/Akt/FOXO1 signaling elements.γ Secretase inhibitor BMS-708163 reverses resistance to EGFR inhibitor via the PI3K/Akt pathway in lung cancer.Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling.Notch Signaling in Vascular Smooth Muscle Cells.
P2860
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P2860
Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Notch activation induces Akt s ...... is in breast epithelial cells.
@en
Notch activation induces Akt s ...... is in breast epithelial cells.
@nl
type
label
Notch activation induces Akt s ...... is in breast epithelial cells.
@en
Notch activation induces Akt s ...... is in breast epithelial cells.
@nl
prefLabel
Notch activation induces Akt s ...... is in breast epithelial cells.
@en
Notch activation induces Akt s ...... is in breast epithelial cells.
@nl
P2093
P1433
P1476
Notch activation induces Akt s ...... sis in breast epithelial cells
@en
P2093
Andrew P Gilmore
Keith Brennan
Olivier Meurette
Rebecca Rock
Spyros Stylianou
P304
P356
10.1158/0008-5472.CAN-08-3478
P407
P577
2009-06-02T00:00:00Z