The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis. - Wikidata - awgldk - TriplyDB

The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis.

The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis.

http://www.wikidata.org/entity/Q39843664

about

Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia The roles of TTP and BRF proteins in regulated mRNA decay The Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate Response Steering tumor progression through the transcriptional response to growth factors and stroma Physiological networks and disease functions of RNA-binding protein AUF1 The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases The impact of the Cancer Genome Atlas on lung cancer.ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production Destabilization of the ornithine decarboxylase mRNA transcript by the RNA-binding protein tristetraprolin ZFP36L1 negatively regulates erythroid differentiation of CD34+ hematopoietic stem cells by interfering with the Stat5b pathway Posttranscriptional regulation of cancer traits by HuR Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation Tristetraprolin: a weapon against HPV-induced cervical cancer?The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase.Impact papers on aging in 2009.Stability of the LATS2 tumor suppressor gene is regulated by tristetraprolin Regulation of the mRNA half-life in breast cancer Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements.Tristetraprolin represses estrogen receptor α transactivation in breast cancer cells Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1.EGF activates TTP expression by activation of ELK-1 and EGR-1 transcription factors Mammary differentiation induces expression of Tristetraprolin, a tumor suppressor AU-rich mRNA-binding protein.RNase L attenuates mitogen-stimulated gene expression via transcriptional and post-transcriptional mechanisms to limit the proliferative response Suppression of laser-induced choroidal neovascularization by intravitreal injection of tristetraprolin.Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs.Tristetraprolin inhibits the growth of human glioma cells through downregulation of urokinase plasminogen activator/urokinase plasminogen activator receptor mRNAs Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells.Computational challenges, tools, and resources for analyzing co- and post-transcriptional events in high throughput.CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin Stress granules, P-bodies and cancer.Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.Drosophila eyes absent is a novel mRNA target of the tristetraprolin (TTP) protein DTIS11 Ectopic over-expression of tristetraprolin in human cancer cells promotes biogenesis of let-7 by down-regulation of Lin28 Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells.The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes.Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state MicroRNA and AU-rich element regulation of prostaglandin synthesis Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression The role of tristetraprolin in cancer and inflammation.

P2860

Q24598616-4A7A0DA2-8931-49B0-83AF-D5EB9663EB6C Q24632890-F560BBF8-7093-4BD6-9799-39833C948EAE Q24633013-0E0DD084-4235-481B-976F-42127B980070 Q26772138-7A739DA2-1408-44E2-971B-33CCE6170F8C Q26865967-5E8B5C08-B78C-4DF1-82F6-3E77778E7FAC Q27693879-163D840D-3B6A-42A8-9151-C8DC6B8B295D Q28076811-A1980C0A-704C-4326-B6A1-0854094C06A5 Q28084190-192A5658-C85B-469D-8E44-360C0E364282 Q28115802-59D50065-8716-4C68-9187-E6F7585E93EC Q28115940-DC2D17F8-23D3-445F-ABE0-4F68C0D8206E Q28119162-DF4A6CA5-D20E-4818-87CC-453978932C55 Q28248667-D31DDC60-0D5B-4512-A90E-BEA3CC3C328C Q33588805-4FC91D63-9DF8-4DC5-A086-9843016D13A6 Q33627848-0ACC9F79-2AE6-47F3-B776-D8BBDAC03F11 Q33627886-F7B50029-5131-4E09-A0D3-98C77913A4FD Q33854215-E3090B49-30E8-42DD-A88A-9FBA3DDD8EAE Q33885061-456ADB27-0814-450D-AA32-99AEA12BA6B9 Q34023658-CAB3D7AB-04C2-4533-99AC-73B4826E7854 Q34065213-E5B299F1-86BB-443E-BBC9-AF6187B50C5A Q34075981-011C844B-6050-4F0E-BCCA-A1DEA49F677F Q34193713-ADA344FC-29F0-44AC-A591-8089D319C536 Q34203752-E605D6B0-BB66-4BEB-8264-5B8BFD4E1A87 Q34411695-30135E32-B299-426E-AC17-021A458E0FCF Q34580412-9774742B-1608-452A-B463-6F367DF024B5 Q34735778-F4A0C48F-AF9B-4F4C-B861-72052E8F62E8 Q35087731-6C60F199-F2F2-45F0-8464-A2D0F350D3C3 Q35093788-07967956-D4DB-4A62-9C1E-6669A2758C50 Q35210986-7ACFA82D-50D0-4364-BA6F-6FE18F0B1775 Q35417365-217434E5-C812-4EC2-A7F5-44A0B327B05D Q35534230-AABA60E7-111A-4220-A87D-E4C34C815E1A Q35689148-DF57B2C1-6942-4D6D-A57A-38A864191DE8 Q35757055-102A4454-65F1-46F4-BFD4-EAB223EBF9FF Q35926324-BBF0683C-89CD-4829-872E-2A08D168A814 Q35956057-D5B5170D-EF4E-4AD4-9410-B80554B87AB8 Q36139104-2FDA1BE3-1262-4609-9F56-94FC90BD3D69 Q36174568-33C656A8-67DA-4227-8140-58F58332E8DC Q36174961-8664EBB9-62EA-4A87-BF5A-D7A79441F1DB Q36249379-66552DE9-D27F-46FE-AF70-B9CD0A40E232 Q36281733-6AEE251A-7D58-461D-9789-530E47DEA791 Q36290434-2EACE303-15EC-4ADE-A8D5-77285ED2E646

P2860

The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis.

http://www.wikidata.org/entity/Q39843664

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

The mRNA-destabilizing protein ...... notypes and patient prognosis.

@en

The mRNA-destabilizing protein ...... notypes and patient prognosis.

@nl

type

label

The mRNA-destabilizing protein ...... notypes and patient prognosis.

@en

The mRNA-destabilizing protein ...... notypes and patient prognosis.

@nl

prefLabel

The mRNA-destabilizing protein ...... notypes and patient prognosis.

@en

The mRNA-destabilizing protein ...... notypes and patient prognosis.

@nl

P1433

Q39843664-AA43F9DD-CE16-4CBD-AACE-CE357CE9C4FA

P1476

Q39843664-E2067889-7459-49F0-9E86-AAA00DD84C43

P2093

Q39843664-1975A5E5-EE88-4079-87CE-A69E26F40E14

Q39843664-61F1B48D-59B8-4F8B-9187-E9EA10FDCB79

Q39843664-76DE2151-C1FC-4211-B1A9-768DB30BBF99

Q39843664-C5F73DCD-1923-4EC0-B733-7E5A6D533107

Q39843664-D381D1D2-E82D-4785-964B-0DF79177E594

P2860

Q39843664-019617AA-CAE7-4501-AB48-3BF232CDAB9B

Q39843664-08BC643F-26F1-4AD6-B263-1BA4CFF67592

Q39843664-19EB8168-8B9F-43C6-AC4C-8EE031243D3F

Q39843664-1B50555E-F334-4C99-ABA1-58D8D6CCE8C7

Q39843664-341C6DEE-2C59-4B8C-B141-25B954F0D2D1

Q39843664-36E59017-6E14-49AA-9B88-3D1771C22FE7

Q39843664-3719C480-F119-4E0B-9AC4-DFCD5B618CD9

Q39843664-41B23A14-27C5-4F6D-8B65-171ACBB7EF49

Q39843664-443F8BD0-BB0C-4A04-90A7-BF7658F4C3B6

Q39843664-48223534-E8B9-4DAF-AB7D-D12E3809BEEE

P304

Q39843664-4F0D1139-92AC-4CB4-A4C2-B4A172835246

P31

Q39843664-19188D80-E664-49BE-ADA5-BEB77ACFEAD3

P356

Q39843664-B7B6393B-EB97-48F1-B429-FD6C340FB203

P407

Q39843664-606A9729-A0C8-421E-86B6-DB6A9174BD5B

P433

Q39843664-82671975-D12A-4952-BE94-86B7A591FCC9

P478

Q39843664-76446328-9AED-4474-9A42-DADFEDCC115C

P50

Q39843664-93EC47AF-2FCB-44CA-88D3-8707074C88FD

P577

Q39843664-A19A4770-59B4-420D-802E-C08057727AD9

P5875

Q39843664-590C7F9C-8F29-4D0D-BDCC-B43F0B7351ED

P698

Q39843664-72B4F6B8-89F2-4D8A-BCB2-B6D0788FFBF3

P932

Q39843664-5108E57C-1628-4233-815A-DDA8A94E87F9

P356

0008-5472.CAN-08-4238

P1433

Cancer Research

P1476

The mRNA-destabilizing protein ...... notypes and patient prognosis.

@en

P2093

Gerald M Wilson

http://www.w3.org/2001/XMLSchema#string

Nadim Alkharouf

http://www.w3.org/2001/XMLSchema#string

Perry J Blackshear

http://www.w3.org/2001/XMLSchema#string

Sarah E Brennan

http://www.w3.org/2001/XMLSchema#string

Yuki Kuwano

http://www.w3.org/2001/XMLSchema#string

P2860

The Hallmarks of Cancer

Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs

A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells

AU-rich elements and associated factors: are there unifying principles?

ARED 3.0: the large and diverse AU-rich transcriptome.

Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up

PACT is a negative regulator of p53 and essential for cell growth and embryonic development

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover

AU-rich elements: characterization and importance in mRNA degradation

P304

5168-5176

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/0008-5472.CAN-08-4238

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

69

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-06-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26261837

http://www.w3.org/2001/XMLSchema#string

P698

19491267

http://www.w3.org/2001/XMLSchema#string

P932

2724875

http://www.w3.org/2001/XMLSchema#string