Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity.
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Identification and characterization of a novel component of the human minichromosome maintenance complexEssential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cellsInteractions of the human MCM-BP protein with MCM complex components and Dbf4MCM-BP regulates unloading of the MCM2-7 helicase in late S phaseStability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycleIdentification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gammaPreventing re-replication of chromosomal DNA.Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteinsA Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replicationTwo mcm3 mutations affect different steps in the initiation of DNA replication.Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture.Plasticity in eucaryotic 20S proteasome ring assembly revealed by a subunit deletion in yeastMammalian Mcm2/4/6/7 complex forms a toroidal structureMutations in subdomain B of the minichromosome maintenance (MCM) helicase affect DNA binding and modulate conformational transitionsA potential role for mini-chromosome maintenance (MCM) proteins in initiation at the dihydrofolate reductase replication origin.The Methanobacterium thermoautotrophicum MCM protein can form heptameric rings.Cross-linking immunoprecipitation-MS (xIP-MS): Topological Analysis of Chromatin-associated Protein Complexes Using Single Affinity Purification.Differential requirements for MCM proteins in DNA replication in Drosophila S2 cellsThe effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 functionControl of chromosomal DNA replication in the early Xenopus embryo.Mammalian nuclei become licensed for DNA replication during late telophaseThe ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by gemininReplication licensing--defining the proliferative state?Characterization of Schizosaccharomyces pombe mcm7(+) and cdc23(+) (MCM10) and interactions with replication checkpoints.Minichromosome maintenance helicase activity is controlled by N- and C-terminal motifs and requires the ATPase domain helix-2 insert.Microarray gene expression analysis of tumorigenesis and regional lymph node metastasis in laryngeal squamous cell carcinoma.Eukaryotic MCM proteins: beyond replication initiation.The dynamics of replication licensing in live Caenorhabditis elegans embryos.Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity.The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation.The fission yeast minichromosome maintenance (MCM)-binding protein (MCM-BP), Mcb1, regulates MCM function during prereplicative complex formation in DNA replication.Geminin becomes activated as an inhibitor of Cdt1/RLF-B following nuclear import.Non-proteolytic inactivation of geminin requires CDK-dependent ubiquitination.The Mcm complex: unwinding the mechanism of a replicative helicase.Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses.CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosisMechanisms and regulation of DNA replication initiation in eukaryotes.Essential role of MCM proteins in premeiotic DNA replication.Nearest neighbour analysis of MCM protein complexes in Drosophila melanogaster.
P2860
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P2860
Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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name
Sequential MCM/P1 subcomplex a ...... eplication licensing activity.
@en
Sequential MCM/P1 subcomplex a ...... eplication licensing activity.
@nl
type
label
Sequential MCM/P1 subcomplex a ...... eplication licensing activity.
@en
Sequential MCM/P1 subcomplex a ...... eplication licensing activity.
@nl
prefLabel
Sequential MCM/P1 subcomplex a ...... eplication licensing activity.
@en
Sequential MCM/P1 subcomplex a ...... eplication licensing activity.
@nl
P2860
P356
P1476
Sequential MCM/P1 subcomplex a ...... eplication licensing activity.
@en
P2093
T A Prokhorova
P2860
P304
P356
10.1074/JBC.275.4.2491
P407
P577
2000-01-01T00:00:00Z