Anticancer peptide CIGB-300 binds to nucleophosmin/B23, impairs its CK2-mediated phosphorylation, and leads to apoptosis through its nucleolar disassembly activity.

Anticancer peptide CIGB-300 binds to nucleophosmin/B23, impairs its CK2-mediated phosphorylation, and leads to apoptosis through its nucleolar disassembly activity.

Item
http://www.wikidata.org/entity/Q39856347
NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingNucleophosmin: from structure and function to disease developmentMolecules that target nucleophosmin for cancer treatment: an updateProtein kinase CK2 and human malignant tumorsOptimizing CIGB-300 intralesional delivery in locally advanced cervical cancer.Synergistic interactions of the anti-casein kinase 2 CIGB-300 peptide and chemotherapeutic agents in lung and cervical preclinical cancer models.Elucidation of motifs in ribosomal protein S9 that mediate its nucleolar localization and binding to NPM1/nucleophosminBiophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11.Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications.Casein kinase: the triple meaning of a misnomer.The synthetic peptide CIGB-300 modulates CK2-dependent signaling pathways affecting the survival and chemoresistance of non-small cell lung cancer cell linesPharmacologic inhibition of the CK2-mediated phosphorylation of B23/NPM in cancer cells selectively modulates genes related to protein synthesis, energetic metabolism, and ribosomal biogenesis.Sensitivity of tumor cells towards CIGB-300 anticancer peptide relies on its nucleolar localization.Identification and characterization of a bactericidal and proapoptotic peptide from Cycas revoluta seeds with DNA binding properties.Immunopharmacology 2011: an updated report of clinical achievements and perspectives.
P2860

Anticancer peptide CIGB-300 binds to nucleophosmin/B23, impairs its CK2-mediated phosphorylation, and leads to apoptosis through its nucleolar disassembly activity.

Item
http://www.wikidata.org/entity/Q39856347
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Anticancer peptide CIGB-300 bi ...... ucleolar disassembly activity.
@en
Anticancer peptide CIGB-300 bi ...... ucleolar disassembly activity.
@nl
type
label
Anticancer peptide CIGB-300 bi ...... ucleolar disassembly activity.
@en
Anticancer peptide CIGB-300 bi ...... ucleolar disassembly activity.
@nl
prefLabel
Anticancer peptide CIGB-300 bi ...... ucleolar disassembly activity.
@en
Anticancer peptide CIGB-300 bi ...... ucleolar disassembly activity.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Anticancer peptide CIGB-300 bi ...... nucleolar disassembly activity
@en
P2093
P304
P31
P356
10.1158/1535-7163.MCT-08-1056
P433
P478
P50
P577
P698
P921